- RecruitingPHASE3
The Effect of a Six Week Intensified Pharmacological Treatment for Bipolar Depression Compared to Treatment as Usual in Subjects Who Had a First-time Treatment Failure on Their First-line Treatment.
This study looks at how new treatments for bipolar depression, like different medications, compare to usual care. It's for people whose first treatment for bipolar depression didn't quite work. The aim is to find better ways to help people whose mood swings include significant depression.
For: Bipolar DepressionAustria · Germany · Greece - Ongoing, recruitingTherapeutic use (Phase IV)
Exploring the Pharmacomicrobiomics of Depression
This study looks at how a common antidepressant called venlafaxine affects the germs in your gut and how that relates to your depression symptoms and any side effects you might have. It hopes to understand how gut changes link to treatment results.
For: Major Depressive DisorderNetherlands - Ongoing, recruitingPhase II and Phase III (Integrated)
A Phase 2/3, Multicenter, Randomized, Double blind, Placebo controlled Trial of the Safety and Efficacy of Flexible Doses of SEP 363856 as Adjunctive Therapy in the Treatment of Adults with Major Depressive Disorder.
This study is testing a new medicine, SEP-363856, for adults with major depression who are already taking antidepressants. It aims to see if adding this new medicine helps improve symptoms and if it's safe to use.
For: Adjunctive therapy to antidepressants for the treatment of major depressive disorder (MDD) in adults.Czechia · Bulgaria · Spain