AuthorisedPhase III and phase IV (Integrated)Interventional

Evaluation of a New Pain Management Regime for Oocyte Pick-Up During Fertility Treatment

This research study is testing new ways to help women manage pain during egg collection, which is a key step in fertility treatments like IVF. The main goal is to see how well different pain relief medications work to reduce discomfort during the procedure itself. Researchers will measure pain levels and also look at how satisfied patients are with their pain relief afterwards. They'll also check for any side effects, how quickly patients recover, and the success of the fertility treatment. The study aims to make egg collection a more comfortable experience for those undergoing fertility care.

At a glance

Status

Authorised

Phase

Phase III and phase IV (Integrated)

Sponsor

UZ Brussel

Enrolment target

318

Start

22 Jan 2026

Acute procedural pain associated with oocyte pick-up (oocyte retrieval) in women undergoing IVF/ART.

What is this study about?

This study is investigating different ways to manage pain for women undergoing egg collection for fertility treatment. Egg collection, sometimes called oocyte pick-up, is a procedure where eggs are retrieved from the ovaries, and it can sometimes cause discomfort or pain.

The researchers want to compare various pain relief medications to see which ones are most effective during the procedure. They will carefully measure pain levels throughout the egg collection process. But it's not just about pain during the procedure; they also want to know how satisfied women are with their pain relief in the hours and day afterwards, and if they need any extra pain medication once they go home.

Ultimately, this research aims to find better pain management options so that women undergoing fertility treatment can have a more comfortable experience during egg collection. By improving pain relief, the hope is to make the journey through IVF or similar treatments a little easier.

Key takeaways

This study tries to find better pain relief for egg collection.
It tests various pain medications during IVF procedures.
Pain levels and patient satisfaction are key measures.
Researchers also look at recovery, side effects, and pregnancy outcomes.
The goal is to make fertility treatment more comfortable.

Who may be eligible?

This study is particularly looking for women who are undergoing fertility treatment and will be having an egg collection procedure. You need to be at least 18 years old to take part.

More detailed criteria about your health, any existing conditions you might have, and specific fertility treatment plans would be discussed by the study team. This is to make sure the study is a good fit for you and that taking part would be safe.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

Am I a woman undergoing fertility treatment?
Am I scheduled for an egg collection procedure?
Am I 18 years old or older?
Am I willing to have my pain levels and recovery monitored?

Answer every question to see your result.

What does participation involve?

If you join this study, your experience will focus on how well different pain relief options work during your egg collection. This means you would receive one of the specific pain relief medications being tested before or during your procedure.

During your egg collection, your pain levels would be regularly checked. After the procedure, you'll be asked about your pain and how happy you were with the pain relief. Researchers will also keep an eye on how quickly you recover and if you experience any side effects like nausea or bleeding. They will also follow up on some aspects of your fertility treatment, like pregnancy outcomes, typically up to around 7 weeks after your embryo transfer. The total duration of your active involvement would primarily be around the time of your egg collection and immediate recovery, with some follow-up beyond that.

Potential risks and benefits

Taking part in a study like this might offer the benefit of receiving close monitoring during your egg collection and potentially experiencing improved pain relief compared to standard care, contributing to a better overall experience. However, as with any medication, there's always a chance of side effects, and some of the pain relief options might not work as well for you. The medical team will be closely watching your health throughout. Remember, you can choose to leave the study at any time without it affecting your ongoing medical care.

Locations (1)

Some site locations are approximate. We're improving this — please verify with the trial team before travelling.

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Unverified
Belgium

Common questions

What is 'egg collection'?

Egg collection (or oocyte pick-up) is a procedure to remove eggs from your ovaries, which are then used in fertility treatments like IVF.

Will I know which pain relief I'm getting?

In some studies, you might not know which specific medication you're receiving to ensure unbiased results. The study team will explain how it works.

What happens if I'm still in pain during the procedure?

The medical team will be closely monitoring you and can provide additional pain relief if needed to ensure your comfort and safety.

Will taking part affect my chances of getting pregnant?

The study aims to evaluate pain management without negatively impacting your fertility treatment outcomes. This will be closely monitored.

How long will I be involved in the study?

Your main involvement will be around the time of your egg collection and immediate recovery, with some follow-up for a few weeks afterward.