Comparison of HT Concomitant With RT vs RT Alone in Patients With a Detectable PSA After Prostatectomy

This study is looking for men who have had surgery for prostate cancer, and whose PSA levels have started to rise again after the operation but are not too high. You would need to be generally well, without signs of the cancer having spread to other parts of your body, and have healthy blood test results.

There are also some specific conditions that would prevent you from joining. For example, if your prostate cancer was a different type than common adenocarcinoma, or if you've already had radiotherapy to your pelvis, you wouldn't be able to participate. If you've had certain other serious health conditions, or if you've already been taking hormone therapy for your prostate cancer, you would also be excluded.

If you join this study, you'll be put into one of two treatment groups by chance, like flipping a coin. One group will receive radiotherapy to your pelvis and prostate area. The other group will get the same radiotherapy, plus you'll be given the degarelix hormone therapy for six months. You will have regular appointments and tests to check how you are responding to treatment and to monitor your health. The duration of your participation in the study, including follow-up, will be determined by the study design, but the treatment period is clearly defined.