Continued Access Study for Participants Deriving Benefit in Pfizer-Sponsored Avelumab Parent Studies That Are Closing

This study is specifically for people who are already taking part in certain Pfizer-sponsored Avelumab studies that are about to close. You can join this new programme if your current treatment is really helping you, or if you're currently in the follow-up phase of one of those studies.

You must also be willing to follow specific rules about contraception or avoiding pregnancy to take part. Also, you need to be able to come to all your scheduled appointments and follow the study's plan for treatment and other procedures.

There are a few reasons why you might not be able to join. For example, if you are pregnant or breastfeeding, this study would not be suitable for you. Also, if your doctor or the study organisers think that joining would not be safe or appropriate for you for any medical reason, you would not be able to take part.

If you are eligible, taking part means you'll continue to receive your current study treatment, such as Avelumab, which you were on in the original Pfizer study. You'll have regular hospital visits, just like before, so that the medical team can check how you're doing. These visits will involve health checks, tests, and discussions about any side effects you might be experiencing.

The study will also involve monitoring your safety and tracking your overall health over time. There isn't a set end date for your participation, as it continues for as long as you are benefiting from the treatment and wish to remain in the study, or until your doctor advises otherwise. You'll be given detailed information about your specific treatment plan, expected visits, and any required follow-up.