AuthorisedTherapeutic use (Phase IV)Interventional

Evaluation of ALLERgen Specific Vaccination of DOG Allergic Patients in Swedish Practice - ALLERDOG SWEDEN

This study, called ALLERDOG SWEDEN, is investigating a specific treatment for people who suffer from allergic rhinitis caused by dog allergy. Allergic rhinitis is when you get symptoms like a runny nose, sneezing, and itchy eyes after being around dogs. The researchers want to see if a treatment called Alutard SQ Dog can improve these symptoms over one year. They will test how participants react to dog dander (tiny flakes of skin and fur from dogs) before and after the treatment. This will involve checking for improvements in symptoms like sneezing and itchy eyes, and also looking at how people generally feel about their allergy symptoms. The study is in its final phase, meaning the treatment has already been tested for safety and effectiveness in earlier studies.

At a glance

Status

Authorised

Phase

Therapeutic use (Phase IV)

Sponsor

Karolinska Institutet

Enrolment target

Start

15 Jan 2025

Allergic rhinitis due to dog allergy

What is this study about?

If you suffer from dog allergy, you know how uncomfortable it can be. Symptoms like sneezing, a runny nose, and itchy, watery eyes can really affect your daily life. This study, called ALLERDOG SWEDEN, is specifically looking at a long-term treatment option for adults who experience these symptoms because of dog allergy. The main goal is to see how much improvement people get in their allergy symptoms after using a treatment called Alutard SQ Dog for one year.

The researchers will compare how severe people's symptoms are when they are exposed to dog dander (the tiny bits of skin and fur that cause allergies) before they start the treatment and then again after one year of treatment. They will be using special scores and scales to measure these improvements. They will also keep an eye on any side effects and look at how the treatment might change levels of certain allergy-related substances in the body.

Ultimately, this study aims to provide more information about how effective this specific treatment is in real-world use for people with dog allergies. It's about helping us understand better ways to manage your allergy symptoms and improve your quality of life when you're around your furry friends, or even just in places where dogs have been.

Key takeaways

This study is testing a treatment for dog allergy symptoms.
It aims to see if the treatment reduces sneezing and itchy eyes over one year.
Only adults aged 18 and over with dog allergy can participate.
Participation involves receiving injections and having allergy symptoms checked.
The study helps understand better ways to manage dog allergies.
You can stop participating at any time.

Who may be eligible?

This study is looking for adult volunteers, aged 18 years and older. Both men and women can take part. The main requirement is that you must have allergic rhinitis, which means you get symptoms like a runny nose, sneezing, and itchy eyes specifically because of dog allergy.

There might be other specific health conditions or medications that would prevent you from joining, but these details are usually discussed with the study team. They need to make sure the study is safe for you and that the results will be clear.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

Are you 18 years old or older?
Do you get allergy symptoms like sneezing, runny nose, or itchy eyes specifically because of dogs?
Are you able to commit to a one-year study period?
Are you willing to receive injections as part of the treatment?

Answer every question to see your result.

What does participation involve?

If you decide to take part in this study, you would receive the treatment called Alutard SQ Dog, which is given as an injection. You might also be given other common allergy medications like eye drops, tablets, or nasal sprays to help manage your symptoms during the study. Over the course of one year, you would have appointments where your allergy symptoms are checked before and after being exposed to dog dander. This would involve measuring your symptoms 30 minutes after this exposure. The study also involves checking for any side effects and looking at how your body's immune system responds to the treatment. The total duration of your active involvement in the study would be one year.

Potential risks and benefits

Taking part in a study like this could potentially help reduce your dog allergy symptoms, improving your comfort around dogs. However, as with any medical treatment, there's always a risk of side effects from the injections or other medications, although these are usually mild. The specific details of potential benefits and risks would be fully explained to you before you agree to participate. You have the right to withdraw from the study at any time, for any reason, without it affecting your usual medical care.

Locations (1)

Some site locations are approximate. We're improving this — please verify with the trial team before travelling.

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Unverified
Sweden

Common questions

What is allergic rhinitis?

Allergic rhinitis is when you get allergy symptoms like sneezing, a runny or stuffy nose, and itchy eyes caused by breathing in something you're allergic to, like dog dander.

What is dog dander?

Dog dander refers to the tiny flakes of skin that dogs shed, along with their fur, saliva, and urine. These are common triggers for dog allergies.

What does 'Therapeutic use (Phase IV)' mean?

This means the treatment has already been tested for safety and effectiveness in earlier studies. This phase looks at its long-term effects and how well it works in everyday medical practice.

What is Alutard SQ Dog?

Alutard SQ Dog is the name of the specific treatment being studied. It's a type of allergy shot designed to help reduce your reaction to dog allergens over time.

Will I need to stop taking my current allergy medications?

The study will provide specific instructions about what medications you can and cannot take. You might be given certain eye drops, tablets, or nasal sprays as part of the study.