Active not recruitingOBSERVATIONAL

Tyrosine Allergoid Paediatric and Adult Study

This 5-year study is about a treatment for pollen allergies, including hay fever, itchy eyes, and mild or moderate asthma. It aims to see if the treatment works just as well for children (age 5 and up) as it does for adults. The treatment involves giving small, regular doses of substances similar to tree or grass pollen, aiming to help your body get used to them and reduce allergic reactions. Researchers want to observe the long-term effects of this treatment given throughout the year. The goal is to make sure this treatment is effective and safe across different age groups for those affected by tree or grass pollen allergies.

At a glance

Status

Active not recruiting

Sponsor

Allergy Therapeutics

Enrolment target

320

Start

06 Nov 2020

Estimated completion

01 Oct 2026

Allergic Rhinitis Due to Pollen Allergic Conjunctivitis Allergic Asthma

What is this study about?

This study is looking into a specific treatment for people who suffer from allergies to pollen, whether from trees (like birch, alder, and hazel) or grasses (including rye). These allergies can cause symptoms like sneezing, a runny nose (sometimes called hay fever or allergic rhinitis), itchy, watery eyes (allergic conjunctivitis), and even mild to moderate asthma. The treatment being studied is given throughout the year, meaning it's not just used during pollen season but continuously.

The main aim of this 5-year study is to find out if this treatment works just as well for children as it does for adults. Often, treatments are first tested in adults, but it's important to know they are also effective and safe for younger people. By comparing the results from children and adults, researchers can get a clear picture of its long-term benefits across different age groups. This is important for ensuring that children with pollen allergies have access to effective long-term treatment.

Basically, the study wants to confirm that children (from age 5 upwards) who receive this treatment get the same long-lasting relief from their allergy symptoms as adults do. This understanding helps doctors and patients make informed decisions about managing pollen allergies for many years to come.

Key takeaways

A 5-year study on pollen allergy treatment.
Compares treatment effectiveness in children (5+) vs. adults.
Targets hay fever, itchy eyes, and mild asthma due to tree/grass pollen.
Treatment is given all year round.
Aims for long-term relief from allergy symptoms.

Who may be eligible?

To be able to take part in this study, you or your child must be at least 5 years old. You should have been diagnosed with an allergy to either grass and rye pollen or birch, alder, and hazel pollen. This allergy should be causing symptoms like hay fever, itchy eyes, and/or mild to moderate asthma. Importantly, the decision to start this specific treatment must have already been made by your doctor before you consider joining the study.

There are also some reasons why you or your child might not be able to join. For example, if you've had similar allergy treatments for tree or grass pollen in the last 5 years, you won't be eligible. Also, if your doctor only plans to use this treatment for a short time before pollen season, instead of all year round, you wouldn't be able to participate. Lastly, if you have any other health conditions that are listed in the treatment's official information, you also wouldn't qualify for this study.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

Are you or your child aged 5 years or older?
Do you have hay fever, itchy eyes, or mild/moderate asthma from tree or grass pollen?
Has your doctor already decided this specific allergy treatment is right for you?
Have you NOT had an allergy treatment (like this one) for tree or grass pollen in the last 5 years?
Is your doctor planning for you to have this treatment all year round, not just before pollen season?
Do you have none of the health conditions listed in the treatment's official information?

Answer every question to see your result.

What does participation involve?

The study will last for 5 years. If you join, you will be receiving the specific allergy treatment throughout the year, as decided by your doctor. The study will involve regular check-ups and assessments to see how well the treatment is working for your allergy symptoms over this long period. The exact number of visits and the types of tests will be explained in detail by the study team, but they will be designed to monitor your health and the effectiveness of the treatment.

Potential risks and benefits

Taking part in this study could potentially offer long-term relief from your pollen allergy symptoms through a structured treatment plan. However, as with any medical treatment, there might be side effects, which will be fully explained by the study team. You always have the right to withdraw from the study at any time, for any reason, without it affecting your usual medical care. The study team will discuss all potential benefits and risks with you in detail before you make a decision.

Locations (1)

Universitätsklinikum Augsburg
Verified postcode
Augsburg, Germany

Common questions

What kind of allergies is this study looking at?

This study is for people with allergies to pollen from trees (like birch, alder, and hazel) or grasses (including rye).

What symptoms do I need to have to be in the study?

You should have symptoms like hay fever (runny nose, sneezing), itchy eyes, and/or mild to moderate asthma caused by these pollen allergies.

How long will the study last?

The study is planned to last for 5 years.

Can children take part in this study?

Yes, children aged 5 years and older can take part, as the study aims to compare results between children and adults.

What if I've had allergy treatment before?

If you've had similar allergy treatments for tree or grass pollen in the last 5 years, you won't be able to join this study.