Ongoing, recruitingTherapeutic exploratory (Phase II)Interventional

Blomia tropicalis allergen extract. Determination of the vivo histamine equivalent prick test units

This study is looking for a better way to assess allergies to a common dust mite called Blomia tropicalis. If you have this allergy, you might be able to take part. Researchers will use a skin prick test, a common and usually safe method. They will put tiny drops of different strengths of the Blomia tropicalis allergen on your skin, along with a 'positive' control (something known to cause a reaction) and a 'negative' control (something that shouldn't cause a reaction). They'll then measure the size of any bumps that appear on your skin. This helps them work out the best way to measure how sensitive people are to this allergen, making future allergy treatments more accurate.

At a glance

Status

Ongoing, recruiting

Phase

Therapeutic exploratory (Phase II)

Sponsor

Inmunotek S.L.

Enrolment target

Start

20 Oct 2025

Allergy to Blomia tropicalis

What is this study about?

This study is about finding the best way to measure how sensitive people are to the Blomia tropicalis dust mite allergen. Blomia tropicalis is a tiny creature, similar to other dust mites, that can cause allergic reactions in some people. If you have an allergy to this particular dust mite, you might experience symptoms like sneezing, a runny nose, itchy eyes, or even asthma.

The main goal of this research is to figure out the right 'dose' or strength of the Blomia tropicalis allergen to use in a skin prick test. This test helps doctors understand how much a person reacts to an allergen. By finding the most accurate way to do this, scientists hope to improve how allergies to Blomia tropicalis are diagnosed and how future treatments for this allergy are developed.

This study is in an early phase, sometimes called 'Phase II'. This means it's one of the first times this specific way of measuring sensitivity is being carefully studied in people. Researchers will also be keeping a close eye on any side effects or reactions to make sure the testing method is safe.

Key takeaways

Study aims to improve allergy testing for Blomia tropicalis dust mite.
Participation involves a simple skin prick test.
Looking for adults aged 18+ with a Blomia tropicalis allergy.
No new medication, focus is on finding the right test strength.
Will help scientists develop better diagnostic tools for this allergy.

Who may be eligible?

To take part in this study, you need to be an adult, 18 years old or older. The study is open to both men and women.

The most important thing is that you must have an allergy to Blomia tropicalis. This means you would have previously been diagnosed with this specific allergy. The study is designed to understand how people with this allergy react to different strengths of the allergen.

Quick self-check

Are you 18 years old or older?
Do you have a male or female biological sex?
Have you been diagnosed with an allergy to Blomia tropicalis?
Are you able to attend the study site for a skin prick test?

This is a guide only — the research team will confirm whether you can take part.

What does participation involve?

If you decide to take part, you will have a skin prick test. During this test, a small drop of liquid containing the Blomia tropicalis allergen (in different strengths), or a control substance, will be placed on your arm. A tiny prick will be made through the drop, just deep enough to let a small amount of liquid enter your skin. This is usually done with a special device that barely breaks the skin surface.

Researchers will then measure any small red bumps (called 'wheals') that appear on your skin. They will carefully record the size of these reactions. They will also ask you about any side effects you might experience, both at the site where the test was done and generally. There is no medication involved in this particular study, it's solely focused on the skin test. The total duration of your participation is expected to be short, likely limited to a single visit for the skin prick test and observation.

Potential risks and benefits

The potential benefit of taking part is that you would be contributing to scientific knowledge that could help improve how Blomia tropicalis allergies are diagnosed and treated in the future. As for risks, the skin prick test is generally very safe, but you might experience some temporary itching, redness, or swelling at the test sites. On rare occasions, more widespread allergic reactions can occur, but staff will be on hand to help if needed. You are free to withdraw from the study at any time, for any reason, without it affecting your medical care.

Locations (1)

—
Spain

Common questions

What is Blomia tropicalis?

It's a type of tiny dust mite that can cause allergic reactions in some people, similar to other common dust mites.

What is a skin prick test?

It's a common allergy test where tiny drops of allergen are put on your skin, and a small prick is made to see if a red, itchy bump appears. It usually doesn't hurt much.

Will I receive any new treatment?

No, this study is not testing a new treatment. It's focused on finding the best way to measure allergy reactions using an existing test method.

How long will I need to be at the clinic?

While the specific time will be detailed by the research team, a skin prick test and observation typically take a few hours for a single visit.

What happens if I have a reaction during the test?

The medical team conducting the study is trained to manage any unexpected reactions and will be closely monitoring you throughout the test.