AuthorisedTherapeutic confirmatory (Phase III)Interventional

D. pteronyssinus and D. farinae allergen extracts. Study of the sensitivity and specificity of the prick test diagnostic preparation

This research is looking at two new skin prick tests designed to check for allergies to two specific types of house dust mites (D. pteronyssinus and D. farinae). The main goal is to see how accurate these tests are at identifying who has these allergies. Researchers will put a tiny bit of the dust mite solutions on the skin and measure the small bumps (called wheals) that appear. They will also use standard positive and negative controls for comparison. This study is in the final stages of testing (Phase III) before new treatments or tests can be widely used. They will also be checking for any side effects of the tests.

At a glance

Status

Authorised

Phase

Therapeutic confirmatory (Phase III)

Sponsor

Inmunotek S.L.

Enrolment target

Start

25 May 2026

Allergy to Dermatophagoides pteronyssinus Allergy to Dermatophagoides farinae

What is this study about?

When you have an allergy, your body reacts to something usually harmless, like pollen or dust mites. This study is focusing on allergies to two very common types of house dust mites: Dermatophagoides pteronyssinus and Dermatophagoides farinae. These tiny mites live in our homes and can cause allergic reactions like sneezing, itchy eyes, or asthma symptoms.

Doctors often use a "skin prick test" to find out what someone is allergic to. This involves putting a small drop of a suspected allergen (the substance that causes the allergy) on your skin and then gently pricking the skin so the allergen can get underneath. If you're allergic, you'll usually develop a small red bump, like a mosquito bite, within minutes.

This study is testing new, improved solutions for these skin prick tests to make sure they are very good at identifying allergies to these specific dust mites. By carefully measuring the size of the bumps that appear during the test, the researchers want to make sure the tests give clear and correct results. This helps doctors confidently diagnose dust mite allergies, which is the first step in managing and treating them effectively.

Key takeaways

This study evaluates new skin prick tests for common dust mite allergies.
It aims to improve the accuracy of allergy diagnosis.
Participants will undergo skin prick tests and be monitored for reactions.
Only adults aged 18 and over are eligible.
The study helps develop better diagnostic tools for future use.
It does not involve new treatments, only diagnostic testing.

Who may be eligible?

This study is looking for adults aged 18 years and older. Both men and women can take part.

They are specifically looking for people who are known to have an allergy to Dermatophagoides pteronyssinus (a type of dust mite) or Dermatophagoides farinae (another type of dust mite).

Other specific health conditions or medications might affect whether you can join, but the doctors running the study will check all these details with you.

Quick self-check

Are you 18 years old or older?
Do you have a known allergy to a house dust mite (D. pteronyssinus or D. farinae)?
Are you able to attend the study site for skin prick testing?
Are you comfortable with undergoing a skin prick test?

This is a guide only — the research team will confirm whether you can take part.

What does participation involve?

If you decide to take part, the main part of the study involves having a skin prick test. This is usually done on your forearm. A small amount of different test solutions, including the dust mite extracts and control solutions (one that should cause a reaction and one that shouldn't), will be applied to your skin using a tiny prick. The medical team will then measure the size of any bumps that appear.

They will also keep a close eye on you for any side effects during and after the test, such as redness, itching, or swelling at the test site, or any general reactions. The medical team will tell you how long to expect this all to take. The total duration of your involvement in the study will be relatively short, likely involving one or very few visits.

Potential risks and benefits

Taking part in this study may offer the benefit of contributing to better diagnostic tests for dust mite allergies, which could help many people in the future. The risks associated with a skin prick test are generally mild and temporary, such as itching, redness, or swelling at the test site. Serious allergic reactions are rare but possible, and the study team will be prepared to manage any such event immediately. You are free to withdraw from the study at any time, for any reason, without it affecting your medical care.

Locations (1)

—
Spain

Common questions

What is a 'skin prick test'?

It's a way to check for allergies. A tiny drop of a substance is put on your skin, which is then gently pricked. If you're allergic, a small bump will usually appear.

What are 'Dermatophagoides pteronyssinus' and 'Dermatophagoides farinae'?

These are scientific names for two common types of house dust mites that can cause allergies.

Why is this study important?

It helps make sure the tests doctors use to diagnose dust mite allergies are as accurate and reliable as possible, leading to better care for patients.

Will I get treatment in this study?

No, this study is about testing diagnostic tools, not new treatments. It focuses on how well the allergy tests work.

How long will my involvement in the study last?

Your participation will likely involve a short visit or a few visits over a brief period, mainly for the skin prick test and observation.