Quercus ilex and Quercus robur allergen extracts. Determination of in the vivo histamine equivalent prick test units (HEP).
This study is for people who are allergic to oak trees, specifically two types called Quercus ilex and Quercus robur. Researchers are using a common and quick skin test, called a prick test, to help us better understand these allergies. They will apply tiny drops of liquid containing different strengths of oak pollen extracts to your skin. They'll also use a positive control (histamine, which usually causes a small bump) and a negative control (plain liquid that shouldn't react) to compare. The main goal is to measure the size of any bumps that appear on your skin. This helps scientists work out how strong the reaction is and how to measure oak allergies more accurately, potentially leading to better diagnosis and treatment in the future.
At a glance
What is this study about?
This study is designed for adults who have allergies to common oak trees, specifically an evergreen oak (Quercus ilex) and a common oak (Quercus robur). The main purpose of the study is to understand how different strengths of oak pollen extracts affect people's skin during an allergy test. This information is important because it helps scientists find the best way to measure how sensitive someone is to oak pollen.
To do this, a very common and safe method called a 'prick test' is used. This involves placing a small drop of liquid containing oak pollen extract on your skin, usually on your forearm, and then gently pricking the skin through the drop. This isn't usually painful, feeling more like a light scratch. The researchers will look at how your skin reacts, specifically measuring the size of any small, raised bumps that appear. They will do this with different strengths of oak pollen, as well as with a control liquid that should not cause a reaction and another control liquid (histamine) that is expected to cause a small reaction, to ensure the test is working correctly.
By carefully measuring these skin reactions, the study aims to improve how we diagnose and understand oak allergies. This type of research, known as a Phase II study, is an early step in developing better ways to assess and potentially manage allergies in the future. It's about getting more precise information on how allergic reactions to oak pollen can be consistently measured.
Key takeaways
- The study helps understand oak allergies better using a simple skin test.
- It's for adults with known allergies to certain oak trees.
- You'll have a skin prick test to see how your skin reacts to oak pollen.
- Participation will involve a single clinic visit.
- The risks are minimal, mainly temporary skin reactions.
Who may be eligible?
To be part of this study, you need to be at least 18 years old – there's no upper age limit. Both men and women can take part.
The most important thing is that you must have a known allergy to oak trees, specifically to the pollen from Quercus ilex and Quercus robur. This will likely have been diagnosed by a doctor already.
While this is a general guide, the research team will ask you some specific questions and carry out checks to make sure the study is right for you and that you meet all their requirements. It's safe to assume they will be checking for any other health conditions or medications that might affect the results or your safety in the study.
- Are you 18 years old or older?
- Do you have a confirmed allergy to oak pollen (Quercus ilex and/or Quercus robur)?
- Are you able to attend a clinic for a skin prick test?
- Are you comfortable with undergoing a standard allergy skin test?
This is a guide only — the research team will confirm whether you can take part.
What does participation involve?
If you decide to take part in this study, your involvement will be quite straightforward. You will need to attend a clinic visit where a healthcare professional will perform skin prick tests. This involves applying tiny drops of various liquids, including different strengths of oak pollen extracts, to your forearm. Your skin will then be gently pricked through these drops. This procedure is usually quick and typically causes only a mild, temporary itch or redness.
During this visit, the healthcare team will closely monitor your skin's reactions to the tests, measuring any small bumps that might appear. You won't be given any medication to take home for the study, nor will there be any long-term follow-up appointments directly related to the study measurements after this initial visit. The total duration of your active participation will likely be limited to this one visit, which shouldn't take too long to complete.
Potential risks and benefits
Locations (1)
- —Spain
Common questions
What is a 'prick test'?
It's a common allergy test where a tiny drop of liquid is placed on your skin, and then the skin is gently pricked through the drop. This helps see if your body reacts to the substance, like pollen.
Will this study cure my oak allergy?
No, this study is about understanding and measuring oak allergies better, not about curing them. It helps scientists learn more for future treatments.
How long will my participation in the study last?
Your active involvement will likely be just one visit to the clinic for the skin tests.
Do I have to take any new medicines?
No, you will not be given any study medicines to take. The study only involves skin tests.
Will I get paid for taking part?
The information provided does not specify payment. You should ask the study team about any compensation for time or travel.
How to find out more
Always speak to your GP or specialist before deciding to take part in a study.
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