Prospective, Non-Randomised Clinical Trial to Investigate the BeGraft Aortic Stent Graft System and the BeGraft Peripheral Stent Graft System Treating Aortic-iliac Occlusive Disease

To join this study, people generally need to have a specific type of blockage in the blood vessels from their tummy to their legs that needs treatment. You should also be experiencing symptoms from this blockage, such as pain even when resting, or sores that aren't healing on their own. You need to be at least 18 years old and expected to live for at least two more years.

Your blood vessels also need to look a certain way on scans for the treatment to be possible using these specific stents. For example, the blockage shouldn't be too close to your kidney arteries, and there shouldn't be any fresh blood clots. If you've recently had a heart attack, stroke, or surgery on these specific blood vessels, you likely won't be able to join.

Also, if you're taking part in another study that tests new medical treatments, or if you're a woman who could have children and not using reliable birth control, then you wouldn't be able to join this study.

If you decide to take part, you would first have a detailed check-up to make sure you're suitable for the study. If you are, you would then have the CERAB procedure, which involves placing the stent grafts into your blood vessels. This procedure is usually done through a small cut, often in your groin.

After the procedure, you'll need to attend regular follow-up visits. These visits are important so doctors can check how you're recovering and how well the stent grafts are working. They will likely involve physical examinations and perhaps some scans to look at your blood vessels. You'll need to be willing and able to come to all these planned appointments. The study does not specify an exact total duration, but follow-up appointments would likely be over several months to a year or more. You wouldn't be given any experimental medication, just the stent grafts as the intervention.