RecruitingOBSERVATIONAL

Clinico-biological Collection of Autoimmune, Dysimmune or Auto-inflammatory Dermatological Diseases

This project is collecting blood samples and information from children and adults with skin conditions linked to their immune system (where the body mistakenly attacks itself). This includes conditions like lupus, psoriasis, and other autoimmune, dysimmune, or autoinflammatory skin diseases. The goal is to build a valuable resource for researchers. By studying these samples, scientists hope to discover new 'biomarkers' – signs in the body that can help diagnose these conditions earlier or predict how they will respond to treatment. This information could also lead to entirely new and better treatments, ultimately helping doctors offer more personalised care for patients in the future.

At a glance

Status

Recruiting

Sponsor

University Hospital, Toulouse

Enrolment target

800

Start

06 May 2024

Estimated completion

01 Apr 2034

Autoimmune Bullous Dermatosis Dysimmune Dermatological Diseases Auto-inflammatory Dermatological Diseases Skin Diseases

What is this study about?

Imagine your body's immune system as its own personal army, designed to fight off infections and keep you healthy. Sometimes, this army can get confused and start attacking your own healthy cells by mistake. When this happens in your skin, it can lead to conditions like autoimmune, dysimmune, or autoinflammatory skin diseases. These diseases can be tricky to diagnose and treat, and they affect many people.

This research project is like setting up a special library of information and samples from people who have these types of skin conditions. The aim is to gather detailed clinical information (about your symptoms and how your disease affects you) and biological samples (like blood) from a wide range of patients. This collection will become a vital resource for doctors and scientists around the world.

By carefully studying these samples, researchers hope to uncover new clues about why these diseases happen and how they develop. This could lead to finding new ways to diagnose them earlier, understand why some people respond better to certain treatments than others, and eventually, develop brand new and more effective treatments. The ultimate goal is to improve the lives of people living with these skin conditions by offering more targeted and successful care.

Key takeaways

This study collects information and blood samples from people with immune-related skin conditions.
It aims to improve understanding, diagnosis, and treatment of conditions like lupus, psoriasis, and others.
Participation involves providing blood samples, either new or leftover from routine tests.
It is a collection study, not a drug trial, so no new medications are involved.
Both adults and children (aged 6+) with these conditions may be eligible.
Your involvement helps advance medical science for future patients.

Who may be eligible?

You might be able to take part in this study if you have a skin condition that doctors believe is caused by your immune system, or if they suspect it might be. This includes conditions like autoimmune blistering diseases (e.g., pemphigus), lupus, scleroderma, psoriasis, eczema, or skin problems caused by certain medications.

Both adults and children aged 6 to 99 years old can be considered. You might also be eligible if you are currently receiving or are expected to receive new types of therapy for your skin condition, such as ground-breaking new medicines or cell therapies.

However, you won't be able to join if you are under 6 years old, pregnant, breastfeeding, or if you are under specific legal protection (like guardianship) that prevents you from giving consent for yourself.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

Do I have a skin condition that might be connected to my immune system?
Am I aged between 6 and 99 years old?
Am I NOT pregnant or breastfeeding?
Am I NOT under legal guardianship that prevents me from making my own decisions about medical research?

Answer every question to see your result.

What does participation involve?

If you decide to take part, the main thing you'll be asked for is a blood sample. This might be taken specifically for the study, or if you're already having blood tests as part of your regular treatment, the study may use any leftover blood samples that aren't needed for your routine care. There are no specific study medications involved, as this is a collection study to understand the diseases better. The duration of your participation isn't specified, but it generally involves providing samples at one or more points in time.

Potential risks and benefits

Taking part in this study might not directly benefit you, but the information and samples collected could help future patients by leading to a better understanding, diagnosis, and treatment of these skin conditions. The main risk associated with participation is discomfort or a small bruise from giving a blood sample, similar to any routine blood test. You are always free to change your mind and withdraw from the study at any time without giving a reason, and this will not affect your usual medical care.

Locations (1)

University Hospital
Verified postcode
Toulouse, France· Recruiting

Common questions

What is the main purpose of this study?

The study aims to collect blood samples and information from people with certain skin diseases to help scientists learn more about them and develop new treatments.

What kind of skin conditions are they looking for?

They are looking for people with autoimmune, dysimmune, or autoinflammatory skin diseases, such as lupus, psoriasis, eczema, and other similar conditions.

Will I have to take any new medicines?

No, this study is about collecting samples and information, not testing new medicines. You will continue to receive your usual medical care.

What will happen if I join?

You will be asked to provide blood samples – either specifically for the study or from samples already taken for your routine care.

Can I leave the study if I change my mind?

Yes, you can withdraw from the study at any time, for any reason, and it won't affect your ongoing medical treatment.

How to find out more

Chloé BOST, MD, PhD

bost.c@chu-toulouse.fr 5 61 77 61 44 Official trial record

Always speak to your GP or specialist before deciding to take part in a study.