All studies
Active not recruitingNAINTERVENTIONAL

Light-Therapy in the Treatment of the Acute Phase of the Bipolar Type II Depression

This study aims to discover if light therapy is a safe and effective treatment for people with Bipolar Type II depression, especially when they feel low during the autumn and winter months. Researchers want to see if using a special bright light can help ease depressive symptoms. They are comparing this bright light treatment to a dim light, which acts as a 'dummy' treatment (like a placebo). The study focuses on people who experience depressive episodes between September and mid-March. By carefully studying how people respond, the researchers hope to find new ways to help those living with Bipolar Type II depression.

At a glance

Status
Active not recruiting
Phase
NA
Sponsor
Douglas Mental Health University Institute
Enrolment target
50
Start
01 Jan 2008
Estimated completion
01 Aug 2026

What is this study about?

This research is looking into whether light therapy can be a helpful and safe treatment for people who have Bipolar Type II disorder and are experiencing a depressive episode. Many people with Bipolar Type II find that their depression gets worse during the autumn and winter months, from September to mid-March.

While light therapy has shown promise for other types of depression, especially seasonal depression, there isn't much information about how well it works specifically for Bipolar Type II depression. This study aims to fill that gap. Researchers want to see if using a special bright light can lift people's mood and reduce their depressive symptoms. They are comparing this bright light to a very dim light, which helps them understand if the brightness itself is making a difference, rather than other factors.

The idea is to find out if this simple, non-drug treatment could be a good option for managing these depressive periods, giving people more choices for their care. The study is designed very carefully so that neither the patient nor the person checking their progress knows whether they are getting the bright light or the dim light. This helps make the results as honest and reliable as possible.

Key takeaways

  • The study explores if light therapy helps Bipolar Type II depression.
  • It's for people experiencing depression in autumn/winter (Sept-March).
  • Compares a special bright light to a dim light (placebo).
  • You would use the light for 30 minutes daily in the morning.
  • Aims to find a new, safe treatment option.
  • Carefully designed to be 'double-blind' for reliable results.

Who may be eligible?

To join this study, you would need to have been diagnosed with Bipolar Type II disorder and currently be experiencing a depressive episode. Your depression would need to have started in September or later, and be affecting you quite a bit according to standard mood questionnaires.

You should also be able to understand the study and agree to take part. You must be between 18 and 70 years old.

There are some reasons why you couldn't join. For example, if you have other serious health conditions like uncontrolled diabetes or heart problems, or if you've had mood swings (mania or hypomania) when exposed to bright light before. People who are pregnant, have certain eye conditions (like glaucoma), or have a history of migraines or epilepsy caused by light, also can't take part. It's also important that you aren't misusing alcohol or drugs, and don't have severe thoughts of harming yourself.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

  1. Have you been diagnosed with Bipolar Type II disorder?
  2. Are you currently feeling depressed, and did it start in September or later?
  3. Are you between 18 and 70 years old?
  4. Do you have any serious underlying health conditions or eye problems?
  5. Have you ever had mood swings (mania/hypomania) from bright light or sun exposure?
  6. Are you able to understand and consent to join the study?
Answer every question to see your result.

What does participation involve?

If you decide to take part, you would first have a thorough check-up to make sure the study is right for you. If accepted, you would be randomly assigned to use either a bright light machine or a dim light machine at home. You would use this light for 30 minutes each morning, shortly after you usually wake up. The study would involve regular check-ups to see how your mood is, how you're sleeping, and to monitor for any side effects. These assessments would help the researchers understand if the light therapy is helping. The total length of your participation beyond the initial assessment period isn't specified in detail here, but it would involve consistent daily light therapy and regular follow-up appointments.

Potential risks and benefits

Potential benefits of taking part could include an improvement in your depressive symptoms if the bright light therapy is effective. You would also be contributing valuable information that could help others with Bipolar Type II depression in the future. Potential risks are generally low, but could include developing symptoms of mania or hypomania, experiencing side effects like light-induced headaches, or feeling worse. Your safety is a priority, and the study would be stopped if serious side effects occurred. Remember, you have the right to withdraw from the study at any time, for any reason, without it affecting your usual care.

Locations (1)

  • Douglas Mental Health University Institute
    Verified postcode
    Montreal, Canada

Common questions

What is Bipolar Type II depression?

It's a type of mood disorder where people experience periods of severe depression and also milder elevated moods called hypomania.

What is light therapy?

It involves sitting near a special light box that gives off bright light, similar to natural outdoor light, to help improve mood.

What does 'double-blind' mean in a study?

It means that neither you nor the researchers checking your progress will know whether you are receiving the bright light or the dim 'dummy' light therapy.

What kind of light will I use?

You would use a special light box called a SADelite lamp, either set to bright (10,000 lux) or dim (100 lux).

How long does each light therapy session last?

Each session would last for 30 minutes, done daily in the morning after you normally wake up.

How to find out more

Always speak to your GP or specialist before deciding to take part in a study.

Discussion

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