RecruitingNAINTERVENTIONAL

Evaluation of a Dimensional Adaptation of Good Psychiatric Management (GPM-extended) for the Treatment of Borderline Personality Disorder

This study is looking at an updated approach called GPM-extended for treating Borderline Personality Disorder (BPD) in adults. It's being compared to a standard treatment called classic GPM. The researchers want to find out if GPM-extended, which combines ideas from treatments for other personality challenges, is more effective. They'll measure whether it improves BPD symptoms, personality functioning, emotions, and social skills after one year. Patients will be split into two groups, each receiving weekly care for a year, and their progress will be checked several times. The aim is to develop better, more tailored treatments for personality disorders.

At a glance

Status

Recruiting

Phase

Sponsor

AddiPsy

Enrolment target

154

Start

19 Jun 2024

Estimated completion

01 Dec 2029

Borderline Personality Disorder Narcissism Obsessive Compulsive Personality Disorder Personality Disorder

What is this study about?

This research is looking into better ways to help adults living with Borderline Personality Disorder (BPD). BPD can make it hard to manage emotions, understand who you are, and have stable relationships. The study is comparing two types of talking therapy, both based on something called Good Psychiatric Management (GPM). One is the 'classic' GPM, and the other is a newer, more flexible approach called 'GPM-extended'.

GPM-extended is designed to be more personal, taking into account each person's unique challenges and how their personality difficulties show up. It builds on ideas used for other personality challenges, like those that involve being overly focused on details or having a strong sense of self-importance. The main goal is to see if this more tailored approach leads to greater improvements in BPD symptoms and daily life compared to the classic GPM.

Researchers will follow people who take part for one year, checking in at different points to see how they are doing. This includes looking at how well they manage their emotions, how their personality functions, and their social interactions. The hope is that this study will help develop more effective, personalised treatments for people with personality disorders in the future.

Key takeaways

Compares two talking therapies for Borderline Personality Disorder (BPD).
GPM-extended aims to be a more personalised treatment.
Study lasts one year with weekly sessions and four assessments.
Aims to improve BPD symptoms, emotional control, and social skills.
No new medications are involved in the study.
Recruiting adults diagnosed with BPD and affiliated with French health insurance.

Who may be eligible?

To join this study, you need to be an adult, aged 18 or older. You must also have a diagnosis of Borderline Personality Disorder (BPD) based on a specific set of criteria, and be able to give your full written consent to take part. You also need to be part of the French national health insurance system.

However, there are reasons why you wouldn't be able to join. These include being under 18, having certain other serious mental health conditions like a severe psychotic disorder or a severe eating disorder like anorexia with health risks. If you have a serious problem with substance use that would stop you from attending intensive therapy, or if you're experiencing a manic phase of bipolar disorder, you also can't take part.

Additionally, if you are under legal protection (like a guardianship), or if you wouldn't be able to complete the questionnaires and assessments, you won't be able to join the study. Finally, if you're not part of the French national health insurance system, you won't be eligible.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

Are you 18 years old or older?
Have you been diagnosed with Borderline Personality Disorder (BPD)?
Can you understand and sign a consent form?
Are you NOT currently dealing with severe substance use problems or a manic phase of bipolar disorder?
Are you NOT under any legal protection like a guardianship?
Are you able to complete questionnaires?

Answer every question to see your result.

What does participation involve?

If you decide to take part in this study, you'll be assigned to one of two groups: one receiving GPM-extended and the other receiving classic GPM. Both groups will attend weekly outpatient psychiatric care sessions for a full year. You won't be given any new medication as part of this study, but will continue with your usual psychiatric care.

To see how well the treatments are working, you'll have assessments at the start (this is called 'baseline'), then after 4 months, 8 months, and finally at 1 year. These assessments will involve both talking to a clinician and filling out questionnaires yourself. They will measure your BPD symptoms and other aspects of your psychological well-being. So, in total, you'd be involved for about one year with four assessment check-ins.

Potential risks and benefits

Taking part in this study could offer the benefit of receiving structured psychiatric care for your Borderline Personality Disorder, potentially leading to improved symptoms and overall well-being. There's also the chance to help researchers understand which treatments work best, which could benefit many others in the future. As with any medical study, there's always a small risk of discomfort from discussing sensitive topics during assessments, or the time commitment involved. However, you are always free to withdraw from the study at any time without giving a reason, and your regular medical care will not be affected.

Locations (2)

Clinique Caradoc
Verified postcode
Bayonne, France· Recruiting
Addipsy
Verified postcode
Lyon, France· Recruiting

Common questions

What is Borderline Personality Disorder?

Borderline Personality Disorder (BPD) is a mental health condition that can cause intense emotional swings, difficulties with self-image, and problems in relationships with others.

What is GPM-extended?

GPM-extended is a new, more personalised version of a standard talking therapy for BPD called Good Psychiatric Management (GPM). It's designed to be more flexible and tailored to your specific needs.

How long does the study last?

If you join, the study will last for one year, during which you will receive weekly treatment and have four assessment check-ups.

Will I have to take new medication?

No, this study is about different types of talking therapy (psychiatric management), not medication. You will continue with any medication your doctor has already prescribed.

What if I change my mind about participating?

You are free to leave the study at any point, for any reason, without it affecting your medical care.

How to find out more

Martin Blay, M.D., M.Sc

m.blay@addipsy.com +33472943403 Official trial record

Always speak to your GP or specialist before deciding to take part in a study.