Single-Fraction Very Accelerated Partial Breast Irradiation (sfVAPBI)

This study is for women who have been diagnosed with early breast cancer, specifically very small cancers that haven't spread much. Your cancer must be limited to the breast, and your lymph nodes (glands in your armpit) should either be clear or have only tiny amounts of cancer cells.

To be considered, your cancer needs to be a certain size (less than 3cm) and must have been completely removed during surgery, with clear edges (meaning no cancer cells were left behind). You should also be over 40 years old. There are specific types of breast cancer that are included, and if you have HER2-positive cancer, you'll need to be receiving treatment for that already.

However, this study isn't suitable for everyone. If your cancer is more advanced, if it has spread to distant parts of your body, or if you have specific types of breast cancer that are known to be more aggressive, you might not be able to join. Also, if you're pregnant or breastfeeding, or if you've had breast cancer before, this study wouldn't be right for you.

If you decide to take part in this study, the main part of your treatment would involve a single radiation session. This means you would receive your radiation therapy in one visit, rather than over several. After this main treatment, the study team would follow your progress over time to see how well the treatment worked and to check for any side effects. This would involve regular check-ups, which might include examinations and imaging tests (like mammograms), but these are standard follow-up care that you would receive anyway after breast cancer treatment. The overall duration of your participation would involve these follow-up visits, as doctors want to see the long-term results of this new treatment method.