RecruitingOBSERVATIONAL

Unmasking Concealed Arrhythmia Syndromes

This research is looking for new and improved ways to find a heart rhythm problem called Brugada syndrome. This condition can sometimes be `hidden`, meaning it doesn't always show up on a regular heart tracing (ECG). The study will test whether different types of ECGs, especially wearable heart monitors you can wear over a longer time, can help doctors see this condition more clearly. They are also developing clever computer programs (artificial intelligence) to help analyse these heart tracings. The ultimate goal is to detect Brugada syndrome earlier and better understand the signs that someone might be at risk of heart rhythm problems, so they can receive appropriate care.

At a glance

Status

Recruiting

Sponsor

Imperial College London

Enrolment target

200

Start

09 Sep 2024

Estimated completion

01 Nov 2026

Brugada ECG Patterns Brugada Syndrome (BrS)

What is this study about?

This research study, called `Unmasking Concealed Arrhythmia Syndromes`, is focused on a heart condition known as Brugada syndrome. This condition affects the heart's electrical system and can sometimes lead to dangerous heart rhythms. The problem is that Brugada syndrome can be `concealed`, meaning it doesn't always show up on a standard heart tracing (ECG) and can be hard to diagnose.

The main aim of this study is to discover if new ways of checking your heart's electrical activity can make it easier to find Brugada syndrome. This includes using long-term heart monitoring devices that you wear, similar to smartwatches, and advanced ECG technology. They are also building special computer programmes using `artificial intelligence` to help doctors recognise the patterns of Brugada syndrome on these heart tracings more quickly and accurately.

Ultimately, by improving how we detect Brugada syndrome, doctors hope to better understand who might be at higher risk of experiencing heart rhythm problems. This could lead to earlier diagnosis and help people get the care they need sooner.

Key takeaways

The study aims to detect hidden Brugada syndrome more effectively.
It uses new technologies like wearable heart monitors and AI.
Participation involves different ways of recording your heart's electrical activity.
The goal is to improve diagnosis and risk assessment for heart rhythm problems.
You must be an adult (18-100 years) and give your consent to join.

Who may be eligible?

To take part in this study, you need to be an adult. This means you must be between 18 and 100 years old.

It's very important that you feel well enough and are able to understand what the study involves and agree to take part. This process is called `giving consent`.

Unfortunately, if you are under 18 or over 100 years old, or if you are unable to understand and agree to the study, you won't be able to join this particular research.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

Are you between 18 and 100 years old?
Do you feel you understand what the study involves?
Are you able to agree to take part freely (give consent)?
Are you comfortable wearing a heart monitor for a period of time?

Answer every question to see your result.

What does participation involve?

If you decide to take part, you'll be involved in one of a few different parts of the study. One involves helping to develop the computer programs that recognise Brugada patterns on ECGs. Another major part will involve wearing a special heart monitor (like a small wearable device) that continuously records your heart's electrical activity over a longer period. This will help researchers collect lots of information about your heart rhythm.

There's also an exploratory part of the study that uses a special type of high-frequency ECG to look for specific signs of risk in people with heart rhythm conditions. The exact number of visits or the total time you'll be involved will depend on which part of the study you join, but it will generally involve wearing monitoring devices and potentially some check-ups.

Potential risks and benefits

Taking part in this study may offer the benefit of potentially helping to improve how Brugada syndrome is detected and understood in the future, which could lead to better outcomes for others. For you personally, there's a chance that previously unknown heart rhythm patterns could be detected. Risks are generally low; wearing a monitor might cause minor skin irritation, or you might find it a little inconvenient. You are absolutely free to withdraw from the study at any time, for any reason, without it affecting your medical care.

Locations (1)

Some site locations are approximate. We're improving this — please verify with the trial team before travelling.

Imperial College Healthcare NHS Trust
Verified postcode
London, United Kingdom· Recruiting

Common questions

What is Brugada syndrome?

Brugada syndrome is a heart condition that affects your heart's electrical system, which can sometimes cause dangerous heart rhythms.

What is an ECG?

An ECG (electrocardiogram) is a simple, painless test that records the electrical activity of your heart to check its rhythm and health.

What does a `wearable ECG` mean?

A wearable ECG is a small device, similar to a smartwatch or patch, that you wear on your body to continuously record your heart's electrical activity over time.

What is `artificial intelligence` (AI) in this study?

AI here means computer programs that are being taught to recognise patterns of Brugada syndrome on ECGs, helping doctors analyse the results faster and more accurately.

Will I get paid to participate?

The information provided doesn't specify payment for participation. You should discuss this with the study team if it's a concern.

How to find out more

Keenan Saleh, MBBS

keenan.saleh10@imperial.ac.uk +442033132243 Official trial record

Always speak to your GP or specialist before deciding to take part in a study.