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Enrolling by invitationEARLY_PHASE1INTERVENTIONAL

Effects of Caffeine Ingestion on Morning Cognitive and Muscle Repeated Sprint Performance in Males

This research is investigating whether caffeine can improve morning athletic performance and mental sharpness in men. Our bodies naturally perform better in the evening than in the morning, which can be a problem for athletes who compete early in the day. This study aims to understand if caffeine can help reduce this morning dip in performance. Participants will be divided into three groups: one taking caffeine, another taking a placebo (a dummy pill with no active drug), and a third group taking no pill at all. This approach helps the researchers clearly see caffeine's true effects, separate from any 'placebo effect' where people feel better just because they think they're taking something helpful. The goal is to find out if caffeine can be a useful tool for morning competitors.

At a glance

Status
Enrolling by invitation
Phase
EARLY_PHASE1
Sponsor
Liverpool John Moores University
Enrolment target
15
Start
08 Dec 2025
Estimated completion
25 Mar 2026

What is this study about?

Have you ever felt less energetic or sharp in the mornings, especially when you need to be at your best? Many athletes face this challenge, as their bodies naturally perform better later in the day. For example, things like muscle strength or how quickly you can react can be slightly lower in the morning compared to the evening. This can make a big difference in sports, particularly in early competition rounds.

This study is looking into whether caffeine could be a simple way to help men overcome this morning dip in performance. Researchers are particularly interested in how caffeine affects both physical tasks, like repeated sprints, and mental tasks in the morning. They want to see if caffeine can make athletes feel stronger and think more clearly when they're competing early in the day.

To get clear answers, the study will have three groups: one group will take a caffeine pill, another group will take a dummy pill (a placebo) that looks just like caffeine but has no active ingredient, and a third group will take no pill at all. This way, the researchers can properly compare the results and understand if any improvements are genuinely due to caffeine, or if they might be due to simply expecting to do better. This helps ensure the findings are reliable and useful for athletes.

Key takeaways

  • This study explores if caffeine helps morning athletic and mental performance.
  • It aims to understand why morning performance is often lower than evening performance.
  • Participants will be divided into caffeine, dummy pill, and no-pill groups.
  • The research focuses on healthy men aged 18-35 who train regularly.
  • Findings could help athletes competing in the mornings.

Who may be eligible?

To join this study, you should be a healthy adult man between 18 and 35 years old. You should also be free from any injuries and have at least two years of experience with weight or strength training. It's important that you don't take any regular medications, including pain relievers like ibuprofen, during the study. You also shouldn't drink much caffeine normally – no more than 150mg (about one and a half cups of coffee) per day. Finally, you shouldn't have a strong preference for training at a specific time of day.

There are some reasons why you might not be able to join. For example, if you're experiencing feelings of sadness or depression, have very poor sleep, or have recently worked night shifts or travelled across many time zones, you wouldn't be suitable. People with unusual sleep patterns (very early risers or very late sleepers) or those with heart problems or symptoms of heart disease also can't take part. It's also important that you don't already know a lot about how time of day affects performance, as this could influence the results.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

  1. Are you a man between 18 and 35 years old?
  2. Do you regularly do weight or strength training (for at least 2 years)?
  3. Are you generally healthy and free from current injuries?
  4. Do you normally drink less than 150mg of caffeine per day (about 1-2 small coffees)?
  5. Are you not currently taking any regular medications, including pain relievers?
  6. Do you not have problems with depression, poor sleep, or heart conditions?
Answer every question to see your result.

What does participation involve?

If you decide to take part in this study, you will be asked to visit the research facility on several occasions. During these visits, you will perform various physical and mental tasks in the morning. You will be randomly assigned to one of three groups: one group will take a caffeine pill, another will take a placebo (a dummy pill), and the third will take no pill before the tests. The researchers will carefully measure how you perform in these tasks. You will need to make sure you stick to your usual low caffeine intake throughout the study. The total duration of your involvement in the study will be explained to you in detail by the research team.

Potential risks and benefits

Participating in this study might offer you the benefit of better understanding how caffeine affects your own morning performance. You will also be contributing to scientific knowledge that could help many athletes. Potential risks are generally low, as the caffeine dose is common. However, some people might experience mild side effects from caffeine, such as feeling a bit jittery or having trouble sleeping later. Taking part is completely voluntary, and you are free to withdraw from the study at any time without giving a reason, and it will not affect any medical care you receive.

Locations (1)

  • Tom Reilly Building (LJMU)
    Verified postcode
    Liverpool, United Kingdom

Common questions

What is a 'placebo'?

A placebo is a 'dummy pill' that looks exactly like the real medication but doesn't contain any active ingredients. It helps researchers understand the true effects of the actual drug.

Why are there different groups, like 'no pill'?

Having different groups (caffeine, dummy pill, and no pill) helps scientists see if the caffeine is really making a difference, or if people just feel better because they think they've taken something helpful. This makes the results more accurate.

What does 'repeated sprint performance' mean?

This refers to how well someone can do multiple short bursts of intense exercise, like sprinting, with short breaks in between. It's a key measure for many team sports.

What kind of tests will I do?

You'll likely do a mix of physical tasks, like cycling sprints, and mental tasks designed to measure your thinking skills and attention during the morning sessions.

Will I know if I'm getting caffeine or the dummy pill?

No, typically in these types of studies, neither you nor the researchers will know who is getting what until after the study is complete. This helps to keep the results fair and unbiased.

How to find out more

Always speak to your GP or specialist before deciding to take part in a study.

Interested in taking part?

Register your interest

Share your details and the research team for "Effects of Caffeine Ingestion on Morning Cognitive and Muscl…" will contact you if you may be eligible. Always speak to your GP before agreeing to take part.

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