RecruitingOBSERVATIONAL

Quality of Pediatric Resuscitation in a Multicenter Collaborative

This study is observing children who have a cardiac arrest in hospital to understand how the quality of life-saving chest compressions (CPR) and the care they receive afterwards affect their recovery. Doctors want to find out how factors like the speed and depth of chest compressions, and how much time is spent doing them, link to whether a child survives and how well their brain recovers. The aim is to gather evidence that could help improve CPR techniques and follow-up care for children, ultimately leading to better outcomes for them and their families.

At a glance

Status

Recruiting

Sponsor

Children's Hospital of Philadelphia

Enrolment target

7,000

Start

02 May 2016

Estimated completion

01 Jan 2030

Cardiac Arrest Cardiopulmonary Arrest

What is this study about?

When a child's heart stops beating (a cardiac arrest), it's a very serious emergency. This study is trying to understand how effective the immediate medical care, especially chest compressions (a key part of CPR), and the care given in the days and weeks afterwards, are in helping children recover. Unfortunately, many children who survive a cardiac arrest can be left with problems that affect their brain, which can be very challenging for them and their families.

Researchers are carefully observing children who have a cardiac arrest in various hospitals. They are collecting detailed information about how CPR is performed – for example, how fast and deep the chest compressions are, and how consistently they are given. They are also looking at the care children receive after their heart has started beating again, known as post-cardiac arrest care.

The main goal is to find connections between specific ways CPR is done, particular types of after-care, and whether children survive and recover well, especially in terms of their brain function. By understanding these links better, medical professionals hope to find ways to improve treatments and care, giving more children a better chance of a full recovery.

Key takeaways

This study observes how CPR and hospital care affect children after their a heart stops.
It aims to find out if specific CPR techniques improve survival and brain recovery.
Children receive their normal medical care; the study just collects information.
There are no additional risks or new treatments involved.
The findings could lead to better emergency care for children in the future.

Who may be eligible?

This study is looking at children who receive life-saving chest compressions (CPR) in hospital for at least one minute. To be included, children must have been born after a full-term pregnancy (at least 37 weeks) and be aged 18 years or younger.

There are a few reasons why a child might not be suitable for this study. For instance, if they were already receiving a special type of life support called veno-arterial ECMO at the very beginning of their CPR event, they would not be included.

Essentially, the study wants to observe children of all genders, from birth (full-term) up to 18 years old, who receive CPR in hospital, unless they were already on certain advanced life support before the CPR started.

Quick self-check

Is the person a child (aged 18 or under)?
Was the child born after at least 37 weeks of pregnancy?
Did the child receive chest compressions for at least 1 minute?
Was the child NOT already on certain life support (ECMO) when CPR started?

This is a guide only — the research team will confirm whether you can take part.

What does participation involve?

This is an observational study, which means that children participating won't be given any new treatments or medicines that they wouldn't already be receiving as part of their standard care. Instead, researchers will be gathering information about the care they are already receiving from their medical team. There are no extra visits or assessments specifically for this study. The medical team will simply record details about the CPR given and the care provided afterwards. The total duration of a child's involvement would depend on their individual hospital stay and recovery following a cardiac arrest.

Potential risks and benefits

There are no direct personal benefits for children involved in this study as they will be receiving their usual medical care. The information gathered may, however, help improve future care for other children experiencing a cardiac arrest. Since this is an observational study and no new treatments are being given, there are no additional risks to those already associated with a child's critical medical condition and standard hospital care. Your child's care will not be affected by their involvement or non-involvement in this study. You would always have the right to withdraw your child's data from the study at any time without affecting their medical care.

Locations (61)

Kaiser Permanente
Los Angeles, United States· Recruiting
Cedars-Sinai Medical Center
Los Angeles, United States· Recruiting
Valley Children's Hospital
Madera, United States· Recruiting
Chldren's Hospital of Orange County
Orange, United States· Recruiting
Stanford University
Palo Alto, United States· Recruiting
Rady Children's Hospital
San Diego, United States· Recruiting
Children's Colorado
Aurora, United States· Recruiting
Nemours Children's Hospital
Wilmington, United States· Recruiting
All Children's Hospital
St. Petersburg, United States· Not yet recruiting
Children's Healthcare of Atlanta (CHOA)
Atlanta, United States· Recruiting
Lurie Children's (Children's Hospital of Chicago)
Chicago, United States· Recruiting
University of Chicago, Comer Children's Hospital
Chicago, United States· Recruiting

+49 more sites — see the official record for the full list.

Common questions

What is a cardiac arrest?

A cardiac arrest is when a person's heart suddenly stops beating effectively, meaning blood can't be pumped around the body. This is a life-threatening emergency.

What is CPR?

CPR stands for Cardiopulmonary Resuscitation. It's an emergency procedure that involves chest compressions and rescue breaths to keep blood flowing and oxygen getting to the brain when someone's heart has stopped.

Will my child receive different care if they are in the study?

No, your child will receive the same standard medical care they would normally get. The study is simply observing and recording information about that care.

What does 'observational study' mean?

An observational study means that researchers are watching and collecting information about what is already happening, without trying out new treatments or making changes to care.

How will the results of this study help?

By understanding which aspects of CPR and after-care are most effective, doctors hope to improve guidelines and training, leading to better survival rates and recovery for children in the future.

How to find out more

Vinay Nadkarni, MD, MS

nadkarni@chop.edu 215-590-7430 Official trial record

Always speak to your GP or specialist before deciding to take part in a study.