RecruitingNAINTERVENTIONAL

Effects of Quercetin on Cardiometabolic Outcomes

This study explores a possible natural way to improve heart health and conditions linked to it, collectively known as cardiometabolic syndrome. These conditions, including heart disease and type 2 diabetes, are major health concerns worldwide. Scientists are interested in Quercetin, a natural substance, because dietary changes often carry fewer risks than medicines. While Quercetin has been suggested to help, no strong research has yet compared it directly to a dummy pill (placebo) to see its effects. This trial aims to fill that gap, looking at how Quercetin might help healthy individuals reduce their risk of these common health problems. The goal is to find safe and effective ways to keep people healthy.

At a glance

Status

Recruiting

Phase

Sponsor

University of Central Lancashire

Enrolment target

Start

01 Mar 2024

Estimated completion

01 Dec 2026

Cardiometabolic Syndrome

What is this study about?

Imagine your body's engine and fuel system – that's a bit like your 'cardiometabolic' health. It includes important parts like your heart and how your body handles sugar. Conditions like heart disease and type 2 diabetes are very common and can be serious. Because of this, scientists are always looking for new ways to help people stay healthy and prevent these problems.

One area they're very interested in is natural things we consume. These often come with fewer side effects than traditional medicines. Quercetin is one such natural substance that can be found in some fruits and vegetables. Some early ideas suggest it might be good for your heart and how your body processes energy.

However, to truly know if Quercetin works, we need to test it properly. This study is designed to do exactly that. It's the first time researchers will compare Quercetin to a 'dummy pill' (a placebo) in a careful and organised way. This will help them understand if taking Quercetin can really make a difference to important health measures linked to your heart and metabolism.

Key takeaways

This study investigates a natural substance called Quercetin.
It aims to see if Quercetin can improve heart and metabolic health.
The study compares Quercetin to a dummy pill (placebo).
It's for healthy non-smokers aged 18-65.
Your participation could help future health understanding.
You can withdraw from the study at any time.

Who may be eligible?

To join this study, we're looking for healthy people generally between the ages of 18 and 65. You shouldn't be a smoker, and your body mass index (BMI) should be below 30, which is a measure of your weight relative to your height.

There are also some important reasons why you might not be able to take part. For example, if you are pregnant, have diabetes, or have other uncontrolled health conditions like high blood pressure, this study wouldn't be suitable. We also can't include you if you're allergic to Quercetin, already take a lot of Quercetin in your diet, or regularly take certain medications or antioxidant supplements.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

Are you between 18 and 65 years old?
Are you a non-smoker?
Do you have a healthy weight (BMI less than 30)?
Are you generally healthy and don't have diabetes or uncontrolled blood pressure?
Are you not pregnant?
Are you not regularly taking specific medications or antioxidant supplements?

Answer every question to see your result.

What does participation involve?

The specific details of what taking part involves are usually explained by the study team. Generally, you would have a few visits to the study clinic for health checks and to receive either Quercetin or a placebo (a dummy pill). You would take the assigned pill for a set period. Throughout the study, you might have blood tests, answer questions about your health, and have your blood pressure checked. There would also be follow-up appointments to see how you're doing after the treatment period. The research team will tell you the total length of time you'd be involved in the study.

Potential risks and benefits

Taking part in any study has potential benefits and risks. You might not directly benefit from taking part, but your contribution could help scientists learn more about Quercetin and potentially improve health for others in the future. As Quercetin is a natural substance, serious risks are generally thought to be low, but there is always a chance of side effects or allergic reactions. All potential risks will be fully explained by the study team. Remember, you can always change your mind and withdraw from the study at any time, for any reason, without it affecting your medical care.

Locations (1)

Some site locations are approximate. We're improving this — please verify with the trial team before travelling.

University of Central Lancashire
Verified postcode
Preston, United Kingdom· Recruiting

Common questions

What is cardiometabolic syndrome?

It's a group of health problems, like heart disease, high blood pressure, and type 2 diabetes, that often occur together and increase your risk of serious health issues.

What is Quercetin?

Quercetin is a natural substance found in many fruits, vegetables, and grains. It's being studied for its potential health benefits.

What is a placebo?

A placebo is a 'dummy pill' that looks exactly like the study medication but contains no active ingredients. It helps researchers see if the actual medicine truly has an effect.

Do I have to pay to join?

No, you should not have to pay to participate in a clinical trial. Any study-related treatments or visits are typically covered by the research study.

What if I take other medicines?

It's very important to tell the study team about all medicines and supplements you take, as some might affect your eligibility or how the study treatment works.

How to find out more

Jonathan Sinclair, PhD, DSc

jksinclair@uclan.ac.uk +447875651533 Official trial record

Always speak to your GP or specialist before deciding to take part in a study.