RecruitingOBSERVATIONAL

Carotid Web Associated With Cerebral Infarctions

This study is gathering information about a rare condition called Carotid Web. This condition is a small growth in the main artery to the brain (carotid artery) and can lead to serious strokes. Scientists don't know much about it, especially why it seems to affect some groups more than others. Currently, people with Carotid Web can still have strokes even when taking usual stroke prevention medication. This research aims to collect details from many patients across the UK, including those from overseas territories. By doing this, they hope to get a clearer picture of Carotid Web, how common it is, and help doctors better diagnose and treat it. The ultimate goal is to find better ways to prevent strokes in people with this condition.

At a glance

Status

Recruiting

Sponsor

University Hospital, Bordeaux

Enrolment target

300

Start

19 Jun 2019

Estimated completion

30 Jun 2026

Carotid Arteries

What is this study about?

This study is investigating a rather rare and not very well-known problem called a Carotid Web. Imagine the main artery in your neck that carries blood to your brain, called the carotid artery. A Carotid Web is like a small, unusual growth or flap inside this artery, near where it branches. Although it's rare, when someone has a Carotid Web, it can cause very serious strokes that can have a big impact on a person's health and daily life.

Doctors have noticed that people with a Carotid Web often have strokes again, even when they're taking medicines to prevent blood clots. This suggests that current treatments might not be enough for this specific problem. Because it's not widely understood, it can sometimes be missed or misdiagnosed by doctors, even in special stroke units.

This study aims to bring together information from many patients across different hospitals. By collecting details about people's symptoms, brain scans, and how they recover, researchers hope to get a much better understanding of Carotid Web. This includes learning how common it is, who it affects, and how it causes strokes. This wider view will help doctors learn to spot Carotid Web earlier and develop more effective ways to treat it, ultimately aiming to prevent future strokes.

Key takeaways

This study focuses on a rare stroke-causing condition called Carotid Web.
It aims to collect broad patient data to better understand Carotid Web.
Participation involves sharing your existing medical information, not new tests.
The goal is to improve diagnosis and prevent future strokes.
Your decision to participate is entirely voluntary and won't affect your care.

Who may be eligible?

To be considered for this study, you need to be at least 18 years old. The most important thing is that doctors must have found a Carotid Web in one of your carotid arteries during a scan. Also, you must have had a stroke or a 'mini-stroke' (called a Transient Ischemic Attack or TIA) that doctors believe was caused by this Carotid Web.

Crucially, two expert doctors, a Neurologist and a Neuroradiologist, must agree that what they see on your scans is indeed a Carotid Web. Finally, you, or someone who can make decisions for you if you can't, must agree to share your medical information for the study after reading all the details.

If you are under 18 years old, you cannot take part. Also, if you don't want your information to be included in the study, that's perfectly fine, and you won't be involved.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

Are you 18 years old or older?
Have your doctors found a Carotid Web on one of your scans?
Have you had a stroke or mini-stroke connected to your Carotid Web?
Are you happy for your medical information to be used for this study?

Answer every question to see your result.

What does participation involve?

If you decide to participate, you won't need to attend extra hospital visits or have additional tests beyond your usual medical care. The study involves your specialist stroke unit doctor, who is part of this research, entering your medical information into a secure online database. This will include details about your health, the results of your brain scans, and how you recovered from your stroke or mini-stroke.

Crucially, experts will carefully review your scans to confirm you have a Carotid Web. This means your participation is mostly about allowing your existing medical information to be shared securely for research purposes, without changing your personal treatment plan. The study will follow your progress through your routine medical appointments.

Potential risks and benefits

There are no direct risks to you from taking part in this study, as it only involves collecting information from your existing medical records and scans, without any new tests or treatments. The main potential benefit is that your information, combined with many others, will help doctors learn more about Carotid Web. This better understanding could lead to improved diagnosis and prevention strategies for future patients, potentially saving lives and reducing disability from strokes. Remember, taking part is completely voluntary, and you are free to withdraw your consent at any time without it affecting your medical care.

Locations (1)

CHU de Bordeaux
Verified postcode
Bordeaux, France· Recruiting

Common questions

What is a Carotid Web?

It's a rare, small flap or growth inside one of the main arteries in your neck that supplies blood to your brain, which can increase the risk of stroke.

Why is this study important?

It aims to gather more information about Carotid Web to help doctors better understand, diagnose, and treat it, ultimately preventing strokes in the future.

Will I have to take any new medicines?

No, this study only collects existing medical information and doesn't involve giving you any new medicines or treatments.

Will my doctors know if I don't want to join?

Yes, but your decision will not affect the medical care you receive in any way.

What kind of information will be collected?

Information about your health, scan results, and how you recovered from your stroke or mini-stroke will be collected.

How to find out more

Stéphane OLINDO, M.D

stephane.olindo@chu-bordeaux.fr 05 57 82 12 63 Official trial record

Always speak to your GP or specialist before deciding to take part in a study.