RecruitingNAINTERVENTIONAL

Head-to-Head Comparison of Five Enhanced Depth of Focus IOLs and One Monofocal IOL

This study looks at how well different types of artificial lenses, called IOLs, improve vision after cataract surgery. The main goal is to compare five newer lenses, which extend your range of clear vision, with a standard single-focus lens. Researchers want to know which lens helps you see best at far, middle, and close distances, how satisfied people are with their new vision, and if they still need glasses for everyday tasks. This research is important because it helps people choose the right lens for their lifestyle, like for reading, computer work, or driving, after their cataract operation. Adults aged 22-85 who need cataract surgery in both eyes and meet certain health requirements might be able to take part.

At a glance

Status

Recruiting

Phase

Sponsor

Augenklinik Ahaus G + H GmbH & Co. KG

Enrolment target

180

Start

12 Apr 2022

Estimated completion

01 Jan 2026

Cataract and IOL Surgery IOL Implantation Presbyopia Correction Extended Depth of Focus

What is this study about?

When you have cataract surgery, the cloudy lens in your eye is taken out and replaced with a clear artificial lens, called an intraocular lens or IOL. There are different types of these lenses, and choosing the right one can make a big difference to your vision afterwards. This study is testing six different kinds of IOLs to see how well they work.

Five of these lenses are designed to give you a wider range of clear vision, meaning you might be able to see well at far distances (like driving), at arm's length (like using a computer), and sometimes even up close (like reading). The sixth lens is a standard single-focus lens, which usually gives excellent vision at one distance, but often means you'll still need glasses for other tasks, like reading or using a computer. The study wants to find out which of these lenses offers the best all-round vision and satisfaction for people.

The researchers are specifically interested in how well these lenses help with middle-distance vision. This is important for many daily activities like looking at a computer screen, cooking, or seeing your car dashboard. Because modern life involves a lot of these tasks, glasses for middle vision can be a hassle. This study will help patients and their eye doctors make the best choice for their personal needs, aiming to reduce how much they need to rely on glasses after surgery.

Key takeaways

Compares different artificial lenses (IOLs) for cataract surgery.
Aims to find lenses that give clear vision at far, middle, and close distances.
Looks at patient satisfaction and how often glasses are still needed.
Participants choose their preferred lens type after expert discussion.
Helps doctors and patients make better choices for individual vision needs.

Who may be eligible?

This study is looking for adults between 22 and 85 years old who need cataract surgery in both eyes. To be eligible, you'll need to have the same type of artificial lens put into both eyes.

There are also some health requirements to make sure the study is safe for you and that the results are clear. For example, your eyes need to be generally healthy apart from the cataract, and you shouldn't have other serious eye conditions like advanced glaucoma or certain types of macular degeneration. If you’ve had previous laser eye surgery like LASIK, you likely won't be able to join.

If you have certain medical conditions or are taking medications that might affect your vision or the surgery, you might not be able to participate. Also, if you have very dry eyes that affect your vision, or if there's a chance you'll need other eye operations during the study, you probably won't be eligible. The best way to know for sure if you can join is to talk to your eye doctor, who can check all the specific details.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

Are you between 22 and 85 years old?
Do you need cataract surgery in both eyes?
Are you able to have the same artificial lens put into both eyes?
Are your eyes generally healthy apart from the cataracts (no advanced glaucoma or serious retinal problems)?
Have you not had previous laser eye surgery (like LASIK)?
Are you comfortable filling out questionnaires and attending follow-up appointments?

Answer every question to see your result.

What does participation involve?

If you decide to take part in this study, you will:

* Have cataract surgery on both eyes, usually about 1 to 2 weeks apart. * Have regular eye tests to check your vision at different distances and in various lighting conditions. * Complete questionnaires about the quality of your vision and how well you can do daily activities. * Attend follow-up appointments at 1 day, 1 week, 1 month, and 3 months after your surgery to monitor your progress and vision. The total duration of your active participation in the study will be about 3 months.

Potential risks and benefits

Taking part in this study may offer the benefit of receiving one of the latest artificial lenses designed to improve your vision over a wider range, potentially reducing your need for glasses. You'll also contribute to important research that helps others make informed choices about cataract surgery. As with any surgery, there are always some risks involved, even if small, such as infection or other complications with the eye. The doctors will explain all potential risks of the cataract surgery, which are generally rare. You are free to withdraw from the study at any time without it affecting your usual medical care.

Locations (1)

Augenklinik Ahaus
Verified postcode
Ahaus, Germany· Recruiting

Common questions

What is an IOL?

IOL stands for Intraocular Lens. It's a tiny, clear artificial lens that replaces your natural lens when it's removed during cataract surgery.

What does 'Extended Depth of Focus' mean?

It means the lens is designed to give you a clearer view over a wider range of distances, rather than just one specific distance, hopefully reducing your need for glasses.

Will I definitely not need glasses if I get one of these new lenses?

While these newer lenses aim to reduce your need for glasses, individual results vary. Some people may still need glasses for certain tasks, especially reading small print or intricate close-up work.

How is the lens chosen for me?

You'll discuss the options with your surgeon, learning about the benefits and limitations of each. This study specifically allows you to choose the lens type that best suits your lifestyle and vision needs.

Is the surgery safe?

Cataract surgery is a very common and generally safe procedure. Your surgeon will explain all the potential risks and benefits to you before you consent to any procedure.

How to find out more

dr. med. (Univ. Bud.) Matthias Gerl, MD

m.gerl@augenklinik.de +49 (2561) 9555-301 Official trial record

Always speak to your GP or specialist before deciding to take part in a study.