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Not yet recruitingNot ApplicableInterventional

Using rapid testing in sexual health clinics to support targeted antibiotic treatment

This study is exploring a new, rapid testing method for common sexually transmitted infections (STIs) such as chlamydia, gonorrhoea, and Mycoplasma genitalium. Currently, it takes several days to get test results back from a lab, which often means people are given antibiotics before their diagnosis is confirmed. This can lead to antibiotics being used unnecessarily. Researchers want to see if a quick test, which gives results in about 20 minutes during your clinic visit, can help doctors prescribe the right antibiotics more efficiently. The study also aims to understand if this new testing approach improves patients' experiences and reduces the number of clinic visits needed. It's happening at the Morley Street Sexual Health Clinic in Brighton.

At a glance

Status
Not yet recruiting
Phase
Not Applicable
Sponsor
University Hospitals Sussex NHS Foundation Trust
Enrolment target
242
Start
01 Sep 2026
Estimated completion
30 Nov 2026

What is this study about?

Sexually transmitted infections (STIs) like chlamydia, gonorrhoea, and Mycoplasma genitalium are quite common in the UK, and numbers are increasing. Many people who have these infections don't have any symptoms, but if left untreated, they can lead to serious health issues. When you get tested for an STI, your samples are usually sent to a laboratory, and it can take several days to get the results back. Because of this waiting time, doctors often prescribe antibiotics before they know for sure which infection you have, or even if you have one at all. This can mean antibiotics are sometimes used when they're not really needed, which is something we want to avoid as it can contribute to antibiotic resistance – where antibiotics become less effective over time.

This study is looking at a new, fast test that can give results during your clinic visit, often within about 20 minutes. The main goal is to find out if using this quick test can help healthcare staff decide on the most appropriate antibiotic treatment for you much faster and more accurately. Instead of a 'one-size-fits-all' approach, it helps target the right medication for the right infection.

Beyond just treatment, the study also wants to see if this quicker testing improves your overall experience at the clinic. Will it make things easier for you? Will it mean fewer visits to the clinic? The information gathered will be really valuable in helping to improve sexual health services in the future.

Key takeaways

  • New rapid test for common STIs like chlamydia, gonorrhoea, and Mycoplasma genitalium.
  • Aims for same-day test results and more targeted antibiotic treatment.
  • Could reduce unnecessary antibiotic use and improve patient experience.
  • Participation involves providing a routine sample and a quick questionnaire.
  • Takes place at Morley Street Sexual Health Clinic in Brighton.
  • Low risks, potential for faster results and better care.

Who may be eligible?

This study is looking for adults aged 16 and over who attend the Morley Street Sexual Health Clinic in Brighton. You might be able to take part if you have symptoms that could be caused by chlamydia, gonorrhoea, or Mycoplasma genitalium, or if you've recently had sexual contact with someone who has been diagnosed with one of these infections.

To join, you need to be willing to provide a urine sample or a vaginal swab (if applicable) and understand and agree to the study requirements. You also should not have taken antibiotics in the last two weeks, or urinated within one hour before giving a sample.

People who have already taken part in this specific study before, or who have symptoms of these infections in their rectum, would not be able to participate.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

  1. Are you 16 years old or older?
  2. Are you attending the Morley Street Sexual Health Clinic in Brighton?
  3. Do you have symptoms, or have you been in contact with someone with chlamydia, gonorrhoea, or Mycoplasma genitalium?
  4. Are you willing to provide a urine sample or vaginal swab?
  5. Have you avoided taking antibiotics in the last two weeks?
  6. Have you not urinated in the hour before your clinic visit?
Answer every question to see your result.

What does participation involve?

If you decide to take part, you'll visit the Morley Street Clinic as you normally would. You'll receive information about the study and be asked to provide written consent, which means you understand and agree to participate. A urine sample or vaginal swab will be collected as part of your routine STI testing. This sample will not only be sent to the lab for the usual checks but will also be tested right there in the clinic using the new rapid test, which gives results in about 20 minutes.

You might also be asked to complete a short questionnaire to share your thoughts on your experience with the rapid test. The clinic staff using the test will also provide feedback on how it works in their daily routine. The study is expected to run from May 2026 to June 2027.

Potential risks and benefits

A potential benefit of joining this study is that you might receive your test results and a more targeted treatment plan much faster, possibly during the same clinic visit. This could lead to quicker recovery and less worry. The study also aims to reduce unnecessary antibiotic use, which is a benefit for everyone in the long run. The risks involved are very low; providing a sample might cause slight, temporary discomfort. While there's a small chance of a test result being incorrect or delayed, all routine lab tests will still be carried out to double-check everything, and any unexpected findings will be handled by the clinic as they normally would. Remember, you are free to withdraw from the study at any time without affecting your medical care.

Locations (1)

Some site locations are approximate. We're improving this — please verify with the trial team before travelling.
  • Morley Street Walk-In Sexual Health clinic
    Unverified
    Brighton, England

Common questions

What infections is this study looking at?

The study focuses on common sexually transmitted infections: chlamydia, gonorrhoea, and Mycoplasma genitalium.

Where is the study taking place?

It's taking place at the Morley Street Sexual Health Clinic in Brighton, UK.

Will I get my test results quickly if I participate?

Yes, a key aim of the study is to provide test results from the rapid test within about 20 minutes during your clinic visit.

Who is funding this research?

The study is being funded by Roche Diagnostics.

What if I take part and then change my mind?

You are free to withdraw from the study at any time without needing to give a reason, and it will not affect your medical care.

How to find out more

Natalie St Clair-Sullivan

Always speak to your GP or specialist before deciding to take part in a study.

Discussion

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