Real-World Efgartigimod Effectiveness in CIDP: A Prospective Study
This UK study is all about a medicine called efgartigimod used for a long-term nerve condition known as CIDP (Chronic Inflammatory Demyelinating Polyradiculoneuropathy). Researchers want to see how well this treatment works for people in their everyday lives, outside of a strict clinical trial setting. They are also interested in understanding the typical journey patients go through with their treatment and how often they need to use healthcare services. Because this is not an 'interventional' study, it means that doctors will continue to make treatment decisions with their patients as they normally would, without the study making those choices for them. Each person taking part will be followed for up to two years after they start taking efgartigimod.
At a glance
What is this study about?
This study is designed to learn more about a condition called Chronic Inflammatory Demyelinating Polyradiculoneuropathy, or CIDP for short. CIDP is a rare, long-term condition where your body's immune system mistakenly attacks the protective covering around your nerves. This can lead to muscle weakness, numbness, and tingling, often getting worse over time or coming and going in 'flares'.
The main goal of this particular study is to see how well a new treatment, called efgartigimod, works for people with CIDP in real-world situations. Unlike some studies where patients might be given a specific treatment or a dummy pill, here, doctors will treat their patients with efgartigimod as they usually would, based on what's best for each individual. Researchers will then observe what happens.
They also want to understand the typical care journey for CIDP patients using efgartigimod, from when they start treatment to how they manage their condition over time. This includes looking at how often people need to use healthcare, such as visiting their doctor or specialist, which can help improve care for others in the future. By collecting this information, doctors and researchers hope to get a clearer picture of CIDP and how efgartigimod can help people affected by it.
Key takeaways
- This study helps understand efgartigimod for CIDP in real life.
- It's about your typical treatment journey, not changing it.
- Researchers will learn how people with CIDP use healthcare.
- You must be starting efgartigimod for CIDP to join.
- Your doctor will still make all treatment decisions.
- Participation lasts up to two years.
Who may be eligible?
To join this study, you need to be an adult, at least 18 years old. You must have been diagnosed with CIDP.
It's important that you are planning to start treatment with efgartigimod for your CIDP. Also, you must not have received efgartigimod before.
This study is not for you if your nerve problems are caused by something other than CIDP, or if you are already taking part in another active clinical study that involves a specific treatment or drug.
Could this study suit you?
Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.
- Are you 18 years old or older?
- Have you been diagnosed with CIDP?
- Are you about to start or have you just started efgartigimod for your CIDP?
- Have you never taken efgartigimod before?
- Are your nerve problems definitely due to CIDP and not something else?
- Are you not currently in another medical research study that involves specific treatments?
What does participation involve?
If you decide to take part in this study, you will continue to receive your efgartigimod treatment as prescribed by your doctor, just as you normally would. The study itself won't change your treatment plan or how your doctor manages your CIDP.
Researchers will follow your progress and collect information about your health and how you use healthcare services over time. This will happen for up to two years after you start taking efgartigimod. This just means they'll be keeping an eye on how you're doing and gathering some details about your treatment journey.
Potential risks and benefits
Locations (23)
- PPD VirtualVerified postcodeWilmington, United States· Recruiting
- Jüdisches Krankenhaus BerlinVerified postcodeBerlin, Germany· Recruiting
- Berufsgenossenschaftliches Universitätsklinikum Bergmannsheil GmbHVerified postcodeBochum, Germany· Recruiting
- UK-RUB - Katholisches Klinikum Bochum - St. Josef HospitalVerified postcodeBochum, Germany· Recruiting
- Universitätsklinikum KölnVerified postcodeCologne, Germany· Recruiting
- Universitätsklinikum DüsseldorfVerified postcodeDüsseldorf, Germany· Recruiting
- Universitätsklinikum FrankfurtVerified postcodeFrankfurt, Germany· Recruiting
- UKGM - Universitätsklinikum Gießen und Marburg GmbHVerified postcodeGiessen, Germany· Recruiting
- Universitätsmedizin GöttingenVerified postcodeGöttingen, Germany· Recruiting
- Universitätsklinikum Hamburg EppendorfVerified postcodeHamburg, Germany· Recruiting
- Neurologie Neuer Wall - Dr.Bredow & PartnerVerified postcodeHamburg, Germany· Recruiting
- Medizinische Hochschule HannoverVerified postcodeHanover, Germany· Recruiting
Common questions
What is CIDP?
CIDP is a long-term condition where your body's immune system attacks your nerves, causing weakness and numbness.
What is efgartigimod?
Efgartigimod is a medicine used to treat CIDP. This study is looking at how it works in real-world settings.
Will my treatment change if I join this study?
No, your doctor will continue to manage your CIDP and prescribe efgartigimod as they normally would. The study observes your usual care.
How long will I be in the study?
You will be followed for up to two years after you start your efgartigimod treatment.
Do I have to do extra visits for the study?
The study doesn't involve extra visits beyond your normal medical appointments for CIDP. Researchers will collect information from your existing care.
How to find out more
Sabine Coppieters, MD
Always speak to your GP or specialist before deciding to take part in a study.
Interested in taking part?
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