Effect of Camostat for Kidney Protection in Chronic Kidney Disease (CamKid).
The CamKid study is investigating a medication called Camostat Mesilate to see if it can help protect the kidneys of people living with chronic kidney disease (CKD), especially those who have protein in their urine. This is a Phase II study, meaning it's an early-stage trial trying to find out if the drug is effective and safe. Researchers will measure various things to understand how Camostat affects the kidneys, such as how your body handles salt and water, changes in your body weight, and your blood pressure at home. The main goal is to find out if Camostat can reduce factors that cause kidney damage. This research is important because it could lead to new ways to treat and manage chronic kidney disease.
At a glance
What is this study about?
Imagine your kidneys as very important filters, cleaning your blood and making sure your body has the right balance of salt and water. When someone has chronic kidney disease (CKD), these filters aren't working as well as they should be. This study, called CamKid, is looking at a medicine called Camostat Mesilate to see if it can help protect these filters and slow down the progression of kidney disease.
The researchers are particularly interested in people with CKD who also have proteinuria, which means there's too much protein spilling into their urine. This is often a sign that the kidneys are under stress. The study aims to understand how Camostat works in the body and if it can help the kidneys stay healthier for longer. They will be looking at several things that are good indicators of kidney health.
For example, they will measure how much salt and water your body releases in your urine, as well as your body weight and blood pressure at home. These measurements help the doctors understand if the medicine is making a difference in how your kidneys are functioning and if your body's fluid balance is improving. The hope is that Camostat could offer a new way to prevent kidney damage from getting worse, improving the lives of people with CKD.
Key takeaways
- The CamKid study is looking into a drug called Camostat for kidney protection.
- It's for people with long-term kidney disease who also have protein in their urine.
- Researchers will check how the drug affects salt and water balance, weight, and blood pressure.
- This is an early-stage study to see if the drug is effective and safe.
- Taking part involves regular clinic visits for checks and samples.
- You can stop participating at any time.
Who may be eligible?
This study is open to both men and women who are 18 years old or older. You could be considered for this study if you have been diagnosed with chronic kidney disease.
Specifically, the study is looking for people whose chronic kidney disease includes having protein in their urine. This is a key factor the researchers are focusing on.
There might be other health conditions or medications that would prevent you from taking part, but the study team will discuss all of these details with you if you are interested in joining.
- Are you 18 years old or older?
- Have you been diagnosed with chronic kidney disease?
- Does your kidney disease involve having protein in your urine?
- Are you willing and able to attend regular clinic visits?
- Could you take a study medication as instructed?
This is a guide only — the research team will confirm whether you can take part.
What does participation involve?
If you decide to take part in this study, you would be given the study medication, Camostat Mesilate. This is an early-stage study, so it helps researchers understand how the medicine works.
Throughout the study, you would need to attend regular visits to the clinic. During these visits, doctors and nurses would perform various checks. This could include collecting urine samples to measure things like salt and water, weighing you to track body composition, and checking your home blood pressure readings.
Taking part would also involve giving blood samples so researchers can look at different markers related to kidney function and how the drug is affecting your body. The team will provide a schedule of all visits, tests, and how long the study will last for each participant.
Potential risks and benefits
Locations (1)
- —Denmark
Common questions
What is Chronic Kidney Disease?
Chronic kidney disease (CKD) means your kidneys are damaged and can't filter blood as well as they should. This can lead to health problems over time.
What is proteinuria?
Proteinuria means there is too much protein in your urine. This is often a sign that your kidneys are not working properly.
What is Camostat Mesilate?
Camostat Mesilate is a medication being studied to see if it can help protect the kidneys in people with chronic kidney disease.
What does 'Phase II study' mean?
Phase II means it's an early-stage study to find out if a new medicine is effective and safe before it can be widely used.
Will I get paid to be in the study?
Payment for participation varies between studies. The study team will tell you if any expenses (like travel) are covered or if you will receive compensation.
How to find out more
Always speak to your GP or specialist before deciding to take part in a study.
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