A study to investigate the effect of oral ticagrelor on the pharmacokinetics of oral rosuvastatin when given in healthy participants
This research study is for healthy volunteers and aims to understand how two commonly used medicines interact in the body. One medicine is called ticagrelor, and the other is rosuvastatin. When people take more than one medication, it's important to know if one medicine affects how the other works. This study will check if ticagrelor changes how rosuvastatin is processed by your body. This type of research, known as a human pharmacology study, is an early stage of testing. It helps doctors and pharmacists know how to prescribe these medicines safely and effectively for patients who might need both. By taking part, you'd be helping medical science learn more about how medicines work together.
At a glance
What is this study about?
This research study is designed for healthy volunteers to help us understand how two specific medicines interact in the body. The medicines we're looking at are ticagrelor and rosuvastatin. Ticagrelor is often used to help prevent blood clots, especially after a heart attack or stent placement. Rosuvastatin is a medicine that helps lower cholesterol levels, often prescribed to reduce the risk of heart disease.
When someone takes two different medicines at the same time, it's possible for one medicine to change how the body handles the other. For example, one medicine might make the other medicine stay in the body longer, or leave the body more quickly. This study will help us find out if taking ticagrelor affects how your body processes rosuvastatin. This is really important because it helps doctors and pharmacists know the safest and most effective way to prescribe these medicines when patients need to take both.
By taking part in this early-stage study, you would be contributing valuable information that helps improve how medicines are used. Understanding these interactions ensures that patients get the right dose of each medication and helps prevent any unexpected side effects.
Key takeaways
- Study focuses on medicine interactions in healthy people.
- Investigates ticagrelor and rosuvastatin.
- Helps doctors prescribe medicines more safely.
- Suitable for healthy adults aged 18 and over.
- Participation involves taking medicines and clinic visits.
- You can withdraw at any time.
Who may be eligible?
To join this study, you need to be a healthy person, meaning you don't have any major medical conditions. You must be at least 18 years old, and there isn't an upper age limit. Both men and women are welcome to take part in this research.
What does 'healthy' mean for this study? It means that based on medical checks like blood tests and a physical exam, doctors wouldn't find any significant health problems that could affect how the medicines work or put you at extra risk. The researchers will carry out these checks to make sure it's safe for you.
If you have any long-term medical conditions, even mild ones, or if you're taking any other regular medications, including over-the-counter ones or herbal remedies, you should discuss this with the study team. They will be able to tell you if you're still suitable for the study.
Could this study suit you?
Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.
- Are you 18 years old or older?
- Do you consider yourself generally healthy?
- Are you comfortable visiting a clinic regularly for appointments?
- Are you able to take study medicines as instructed?
- Are you willing to have blood samples taken during the study?
What does participation involve?
If you decide to take part, you'll be given both ticagrelor and rosuvastatin at different times according to a set schedule. The study team will explain exactly how and when to take these medicines. You will need to visit the study clinic regularly. During these visits, the research team will take blood samples to measure how the medicines are being processed by your body. They may also do other health checks like measuring your blood pressure.
They will also keep a close eye on you for any side effects. You'll be asked to report any changes you notice in your health. The total time you'll be involved in the study will be explained to you in detail, including the number of visits and the overall duration from start to finish. There will also be follow-up checks after you stop taking the study medicines to make sure you're well.
Potential risks and benefits
Locations (1)
- —UnverifiedGermany
Common questions
What is the main goal of this study?
The main goal is to see how two medicines, ticagrelor and rosuvastatin, affect each other when taken together in healthy people.
Who can join this study?
Healthy men and women, aged 18 and older, can join this study.
Will taking part benefit my health?
Not directly, as it's a study on healthy volunteers. However, your participation helps medical science improve care for others.
What will I have to do if I join?
You'll take the study medicines and attend regular clinic visits for blood tests and health checks.
Can I leave the study if I change my mind?
Yes, you can leave the study at any time, for any reason, and it won't affect your future medical care.
How to find out more
Always speak to your GP or specialist before deciding to take part in a study.
Discussion
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