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Cutaneous Squamous Cell Carcinoma Staging Study

This study focuses on a common type of skin cancer called cutaneous squamous cell carcinoma (CSCC). While most cases are easily treated and cause no future problems, a small number can be more serious or even life-threatening. Researchers are looking at existing patient information from two UK hospitals concerning CSCC. They want to check how good the current ways of classifying this skin cancer are at predicting whether someone will have a good outcome or if their cancer might spread. The main goal is to find better ways to understand and manage CSCC, ensuring people get the most accurate information and best possible care. Later, the study will try to find even better tools for prediction. This is not a study where you receive new treatments; instead, it uses information already gathered from patients' medical records.

At a glance

Status
Recruiting
Sponsor
Queen Mary University of London
Enrolment target
1,500
Start
01 May 2023
Estimated completion
05 Jun 2028

What is this study about?

This study is about a very common type of skin cancer, known as cutaneous squamous cell carcinoma, or CSCC. You might also hear it called SCC. Most of the time, this cancer is successfully removed with a simple operation, and people make a full recovery without any further problems. However, for a small number of people, the cancer can be more serious. It can sometimes spread to other parts of the body, which doctors call 'metastasis', or even become life-threatening. The medical community is always looking for ways to better understand and manage these trickier cases.

In this study, researchers are looking at information from people who have already been diagnosed and treated for CSCC at two hospitals in the UK. They are not giving anyone new treatments or medicines. Instead, they are reviewing existing patient records to see how well the current methods doctors use to categorise these cancers predict who will do well and who might face more serious issues. These methods are sometimes called 'staging systems'.

The main aim is to improve how doctors manage people with CSCC. If researchers can confirm or improve how doctors predict the behaviour of these cancers, it means doctors can offer more tailored and effective care for each person. This project will first check the existing methods and then, in a separate step, try to find even better ways to predict the outcome for people with CSCC. This will ultimately help ensure that everyone gets the best possible guidance and treatment for their skin cancer.

Key takeaways

  • Focuses on a common skin cancer, CSCC.
  • Looks at existing patient records to improve understanding.
  • Aims to predict which cancers are more serious.
  • No new treatments or patient visits involved.
  • Could help future patients get better care.
  • Your privacy is protected.

Who may be eligible?

This study is looking for information from people who are at least 18 years old and have already been diagnosed with a type of skin cancer called cutaneous squamous cell carcinoma (CSCC).

You wouldn't be included in this study if you have told your doctors that you don't want your medical information to be used for research purposes. Apart from that, most people over 18 who have had CSCC would be considered.

Since this study uses existing medical records and doesn't involve any new treatments or visits, anyone who meets the age and diagnosis criteria and hasn't opted out of research can have their information included.

Quick self-check
  • Are you 18 years old or older?
  • Have you been diagnosed with cutaneous squamous cell carcinoma (CSCC)?
  • Have you *not* told your care team you prefer your medical data not to be used for research?
  • Were you treated at one of the two UK dermatology centres involved?

This is a guide only — the research team will confirm whether you can take part.

What does participation involve?

This study does not involve you directly doing anything or making any changes to your daily life. You won't have any extra hospital visits, new tests, or be given any medication. The researchers are simply looking at information that has already been collected as part of your normal medical care if you have been diagnosed with cutaneous squamous cell carcinoma. They will review your existing medical records to understand more about your cancer and its outcome. Because it's about looking at past information, there's no set duration for your 'participation' in the usual sense.

Potential risks and benefits

Since this study only involves reviewing existing medical records, there are no physical risks to you. Your personal information will be kept private and handled carefully. The potential benefit is that the findings from this study could lead to better ways for doctors to predict the behaviour of cutaneous squamous cell carcinoma, potentially improving care for future patients. You have the right to withdraw permission for your data to be used for research purposes at any time, usually by discussing this with your general practitioner or the hospital staff involved in your care.

Locations (2)

  • Whipps Cross University Hospital
    London, United Kingdom· Recruiting
  • Dr Emilia Peleva
    London, United Kingdom· Active not recruiting

Common questions

What is cutaneous squamous cell carcinoma (CSCC)?

It's a common type of skin cancer. Most cases are treated successfully, but some can be more serious.

Do I need to do anything if I'm in this study?

No, you don't need to do anything. This study looks at existing medical records, not new treatments or visits.

Will I be given new medicine or treatments?

No, this study is not testing any new medicines or treatments. It's about understanding past cases.

Will my personal details be kept private?

Yes, any information from your medical records used in the study will be handled very carefully and kept private.

Why is this study important?

It aims to help doctors better predict how serious CSCC might be, which could improve care for people in the future.

How to find out more

Always speak to your GP or specialist before deciding to take part in a study.

Interested in taking part?

Register your interest

Share your details and the research team for "Cutaneous Squamous Cell Carcinoma Staging Study…" will contact you if you may be eligible. Always speak to your GP before agreeing to take part.

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