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RecruitingNAINTERVENTIONAL

CirrhoCare- Using Smart-phone Technology to Enhance Care and Access to Treatment for Cirrhosis

This study, called CirrhoCare, is for adults with a serious liver condition called decompensated cirrhosis. We want to see if using a special smartphone system, CirrhoCare, can improve their care and be more cost-effective than standard hospital visits. The CirrhoCare system helps people check important health signs like heart rate, blood pressure, weight, and mental sharpness from home. This information is then securely shared with liver doctors who can use it to give more personalised care. By doing this, we hope to reduce the number of hospital visits and improve the lives of people with this condition, especially as liver disease is becoming more common and puts a strain on healthcare services.

At a glance

Status
Recruiting
Phase
NA
Sponsor
University College, London
Enrolment target
214
Start
24 Nov 2023
Estimated completion
31 Jan 2027

What is this study about?

Cirrhosis is a serious liver condition where the liver becomes scarred over time. This can happen for different reasons, like drinking too much alcohol, having a fatty liver, or certain infections. Sadly, deaths from cirrhosis are on the rise, and it's a major reason why people lose working years. When cirrhosis becomes more severe, it's called decompensated cirrhosis. This means the liver isn't working as well as it should, and people can develop problems like fluid build-up, confusion, or infections, often needing urgent hospital trips. Even after leaving the hospital, many people with decompensated cirrhosis go back within a month with new problems.

Currently, people with decompensated cirrhosis need to visit the hospital regularly to make sure their condition isn't getting worse. But with more and more people getting liver disease, specialist liver services are stretched. The CirrhoCare study wants to find a better way to care for these patients. It uses a new system that lets people monitor their health at home using a smartphone app and special devices. These devices measure things like your heart rate, blood pressure, weight, and even your mental sharpness – all things that can change as cirrhosis gets worse.

The information collected at home is sent securely to your liver doctor. This helps them understand how you're doing and allows them to adjust your treatment more quickly and personally, without you always having to come to the hospital. The study will compare this new home monitoring system with the usual hospital care to see if it works better for patients and is also good value for money for the NHS. This could make a big difference for people with decompensated cirrhosis, especially considering the challenges of accessing specialist care.

Key takeaways

  • The study explores a new way to manage cirrhosis using a smartphone.
  • It aims to improve care and reduce hospital visits for people with advanced cirrhosis.
  • Participants will either use the home monitoring system or receive usual care.
  • The study wants to see if home monitoring is effective and good value for money.
  • This could offer a new way to get personalised care for your liver condition.

Who may be eligible?

This study is looking for adults aged 18 or over who have been diagnosed with cirrhosis, regardless of what caused it. Your cirrhosis needs to be at a certain stage, known as 'decompensated cirrhosis', which means you've recently been in hospital for problems like fluid build-up, bleeding, confusion, or infections related to your liver condition. You must also be able to understand the study and agree to take part.

However, some people won't be able to join the study. This includes those with very advanced liver failure, very severe confusion that prevents them from giving consent, active liver cancer, or other serious health problems like severe heart, lung, or kidney disease. If you are on the transplant waiting list or receiving palliative care for fluid in your belly that doesn't respond to treatment, you also won't be able to participate. The study aims to help patients with specific needs, so these rules ensure it's safe and effective for everyone involved.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

  1. Are you 18 years old or older?
  2. Have you been diagnosed with cirrhosis?
  3. Have you recently been in hospital for problems related to your cirrhosis (like fluid, bleeding, or confusion)?
  4. Do you have a smartphone or access to one?
  5. Are you able to agree to take part in the study?
Answer every question to see your result.

What does participation involve?

This study is still in the planning stages ('NA' for phase means it hasn't officially started recruiting or isn't assigned a typical drug trial phase). Once it starts, you would be randomly assigned to either use the CirrhoCare smartphone system for home monitoring or continue with your usual hospital care. If you are in the CirrhoCare group, you would use a smartphone app and special home monitoring devices (like a smart scale to measure weight, and devices for heart rate and blood pressure) to regularly check your health from home. You would likely have follow-up with your liver doctor based on the information collected. The total duration of participation and the frequency of checks or hospital visits would be explained in full detail once the study is actively recruiting.

Potential risks and benefits

Participating in research always has potential benefits and risks. A potential benefit of taking part in the CirrhoCare study is that you might receive new and more personalised care through home monitoring, which could potentially reduce hospital visits and improve your quality of life. This new way of managing your condition could also lead to better outcomes. However, as with any new system, there might be technical issues, or it might not work for everyone. There’s always a risk that the new treatment isn't better than standard care, or in some cases, could even be less effective. You have the right to withdraw from the study at any time, for any reason, without it affecting your usual medical care.

Locations (15)

Some site locations are approximate. We're improving this — please verify with the trial team before travelling.
  • Queen Elizabeth Hospital Birmingham, University Hospitals Birmingham NHS Foundation Trust
    Verified postcode
    Birmingham, United Kingdom· Recruiting
  • Royal Sussex County Hospital, University Hospitals Sussex NHS Foundation Trust
    Verified postcode
    Brighton, United Kingdom· Recruiting
  • Walsgrave General Hospital, University Hospital Coventry & Warwickshire NHS Trust
    Verified postcode
    Coventry, United Kingdom· Recruiting
  • Royal Liverpool University Hospital, Liverpool University Hospitals NHS Foundation Trust
    Verified postcode
    Liverpool, United Kingdom· Recruiting
  • The Royal London Hospital, Barts Health NHS Trust
    Verified postcode
    London, United Kingdom· Recruiting
  • Whittington Hospital, Whittington Health NHS Trust
    Verified postcode
    London, United Kingdom· Recruiting
  • Royal Free Hospital, Royal Free London NHS Foundation Trust
    Verified postcode
    London, United Kingdom· Recruiting
  • St Thomas Hospital, Liverpool University Hospitals NHS Foundation Trust
    Verified postcode
    London, United Kingdom· Not yet recruiting
  • King's College Hospital, King's College Hospital NHS Foundation Trust
    Verified postcode
    London, United Kingdom· Recruiting
  • St George's Hospital, St George's university Hospital NHS Foundation Trust
    Verified postcode
    London, United Kingdom· Recruiting
  • Queen's Medical Centre, Nottingham University Hospitals NHS Trust
    Verified postcode
    Nottingham, United Kingdom· Recruiting
  • John Radcliff Hospital, Oxford University Hospitals NHS Foundation Trust
    Verified postcode
    Oxford, United Kingdom· Recruiting

Common questions

What is cirrhosis?

Cirrhosis is a long-term liver condition where your liver becomes scarred and can't work properly. It can be caused by things like alcohol misuse, fatty liver disease, or certain viruses.

What does 'decompensated' mean for my cirrhosis?

Decompensated means your cirrhosis is more severe and your liver isn't coping well, leading to serious problems like fluid build-up, confusion, or infections that often need hospital care.

What is the CirrhoCare system?

It's a new smartphone-based system and special devices that help you track important health signs like your heart rate, blood pressure, weight, and mental sharpness from home.

Will I still see my doctor if I use CirrhoCare?

Yes, CirrhoCare helps your doctor get more information about your health between visits, allowing them to provide more tailored care, but you will still have medical oversight.

Is CirrhoCare available now?

No, CirrhoCare is currently being studied in a clinical trial to see if it's effective. It's not yet a standard treatment option.

How to find out more

Tasheeka Jeyapalan

Always speak to your GP or specialist before deciding to take part in a study.

Interested in taking part?

Register your interest

Share your details and the research team for "CirrhoCare- Using Smart-phone Technology to Enhance Care and…" will contact you if you may be eligible. Always speak to your GP before agreeing to take part.

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