A Non-interventional, International, Multicentre Clinical Research Study to Build the Largest Collection of Multimodal Data (Including Clinical Data, Imaging Data and Omics Data) in Oncology

This study is looking for samples from people who have been diagnosed with certain types of cancer, specifically Diffuse Large B Cell Lymphoma or other solid tumours. For your sample to be included, you must have been over 18 years old when the sample was originally taken.

The research team also needs to be able to access a specific type of preserved tissue sample (called paraffin-embedded tissue) that was collected during your diagnosis or surgery. This sample needs to be less than 10 years old and contain enough cancer cells for them to perform their detailed tests. They also need to be able to access your associated health information.

Critically, you or your legal representative would need to have given consent for your sample and data to be used for research, or there needs to be other legal approval in place from the hospital's ethics board. Samples where the tissue structure isn't well-preserved, like some fluid-based tests, cannot be used.

If your existing preserved tissue sample and health information are suitable and approved for use, your participation in the MOSAIC study would involve no direct action from you. You wouldn't need to attend any extra appointments, take any new medications, or undergo any additional tests or procedures. The researchers would simply use the leftover portions of your tissue sample that were already collected as part of your standard medical care, along with your health information. There's no set follow-up period or total duration for your involvement, as your contribution is the donation of existing data and samples.