Prevention of dementia using mobile phone applications
Dementia affects millions of people worldwide, but research shows that up to one in three cases could be prevented or delayed by addressing lifestyle and heart health risks. This clinical trial is testing whether a dedicated smartphone app can empower people to manage these risks from home. Researchers are inviting adults aged 55 to 75 who live in specific areas of the UK (Sussex and Greater Cambridge) and have at least two common health risks, such as high blood pressure, high cholesterol, or low physical activity. Participants are randomly placed into one of two groups. One group uses an interactive app with regular support from a health coach. The other group receives standard care alongside a simpler app offering general health advice. Everyone has basic health checks at the start and end of the trial to see if digital coaching helps people stay healthier.
At a glance
What is this study about?
Many people do not realise that the health of our heart and blood vessels is closely linked to the health of our brain. Common conditions like high blood pressure, high cholesterol, type 2 diabetes, being overweight, or not getting enough exercise can increase the long-term risk of developing dementia. Fortunately, making small, steady changes to everyday lifestyle habits can help protect brain health as we get older.
This study, called PRODEMOS, is exploring whether mobile technology can make preventive healthcare easier and more accessible. Rather than expecting people to make frequent trips to a clinic, researchers want to see if an easy-to-use smartphone app can give people the guidance they need to take charge of their own health at home.
Participants are divided into two groups by chance. One group receives an interactive app paired with a remote health coach who offers tailored advice and encouragement. The second group receives a simpler version of the app that provides standard healthy living tips, alongside their usual NHS care. By comparing both groups over 12 to 18 months, the study team hopes to find out whether coach-supported apps are an effective and practical way to lower dementia risk across communities.
Key takeaways
- Tests whether a smartphone app and health coach can help lower dementia risk factors.
- Aimed at adults aged 55 to 75 living in Sussex or Greater Cambridge.
- Requires having at least two lifestyle or heart health risks, such as high blood pressure or smoking.
- Compares an interactive coaching app with a general health information app over 12 to 18 months.
- Free to join, involves no new medications, and does not replace your normal GP care.
Who may be eligible?
This study is open to adults aged between 55 and 75 who own a smartphone and speak good English. In the UK, researchers are particularly looking for people living in parts of Sussex and Greater Cambridge where access to preventive healthcare may be more limited.
To take part, you must have at least two health or lifestyle factors that can affect heart and brain health. These include a diagnosis of heart disease, high blood pressure, high cholesterol, type 2 diabetes, being treated for depression, being overweight, smoking, or not meeting recommended weekly exercise targets (around 150 minutes of moderate activity per week).
You cannot take part if you have already been diagnosed with dementia or have significant memory problems that prevent you from using the app independently.
Could this study suit you?
Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.
- Are you aged between 55 and 75?
- Do you own and regularly use a smartphone?
- Do you live in an eligible area in Sussex or Greater Cambridge?
- Do you have at least two common health risks (e.g., high blood pressure, high cholesterol, type 2 diabetes, smoking, or low exercise)?
- Have you never been diagnosed with dementia?
What does participation involve?
If you join the study, you will take part for between 12 and 18 months. At the start, a researcher will check your blood pressure, measure your height and weight (BMI), and take a blood sample to test your cholesterol levels. You will also complete questionnaires about your daily diet, exercise, mood, and overall quality of life.
You will then be randomly assigned to use either the interactive coaching app or a standard health information app on your phone. No new medications are given as part of this study; it focuses entirely on lifestyle guidance. After 12 to 18 months, you will have your health measurements and questionnaires repeated so researchers can see what changes have occurred.
Potential risks and benefits
Locations (2)
- University of CambridgeApproximateCambridge, England
- Capital Medical UniversityApproximateBeijing, China
Common questions
Do I have to pay to use the app?
No, taking part in the trial and using the study application is completely free of charge.
Will I definitely get a personal health coach?
Not necessarily. A computer randomly decides whether you receive the interactive app with a coach or the standard app with general advice, giving both groups an equal chance.
Do I need to be an expert with technology?
No, but you will need to own a smartphone and feel comfortable using basic apps for messaging and reading information.
Will this replace my normal GP appointments?
No. The study app is designed to support you alongside your regular NHS care, not replace your GP or any treatments you currently receive.
What happens if I decide I no longer want to participate?
You can leave the study whenever you wish. Withdrawing will not affect your relationship with your doctor or the medical care you receive.
How to find out more
Edo Richard
Always speak to your GP or specialist before deciding to take part in a study.
Discussion
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