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Ongoing, recruitingTherapeutic confirmatory (Phase III)Interventional

A Phase 3, Randomized Study to Evaluate the Efficacy and Safety of Pembrolizumab (MK-3475) + Lenvatinib (E7080/MK-7902) + Chemotherapy Compared with Standard of Care as First-line Intervention in Participants with Metastatic Esophageal Carcinoma

At a glance

Status
Ongoing, recruiting
Phase
Therapeutic confirmatory (Phase III)
Sponsor
Merck Sharp & Dohme LLC
Enrolment target
136
Start
25 Jul 2023

What is this study about?

Part 1 (5-Fluorouracil [5-FU] plus cisplatin [FP] and paclitaxel plus cisplatin [TP] Safety Run-in): Number of Participants With Dose Limiting Toxicities (DLTs), Part 1 (FP and TP Safety Run-in): Number of Participants With Adverse Events (AEs), Part 1 (FP and TP Safety Run-in): Number of Participants who Discontinued Study Treatment Due to an AE, Part 2 (Main Study): Overall Survival (OS) in all Participants

Who may be eligible?

Age 18 Years to any · Sex: All

Locations (6)

  • Spain
  • Hungary
  • France
  • Denmark
  • Italy
  • Romania

How to find out more

Always speak to your GP or specialist before deciding to take part in a study.

Discussion

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