RecruitingOBSERVATIONAL

PATAKESS Protocol : Clinical and Biological Analysis of Exocrine Pancreatic Tumors

The PATAKESS study is investigating exocrine pancreatic cancer, which is a very serious type of cancer. It's not a new treatment trial, but rather a research project looking back at information and tissue samples already collected from patients at a hospital in France since 2010. The main goal is to connect what they see in the tumour samples itself (like its biology) with what happened to the patients clinically. This research is important because pancreatic cancer is often aggressive and hard to treat. By understanding more about how these tumours grow and interact with the body, scientists hope to find better ways to fight it in the future, ultimately improving the chances for people affected by this disease.

At a glance

Status

Recruiting

Sponsor

Centre Leon Berard

Enrolment target

300

Start

01 Sep 2020

Estimated completion

01 Apr 2028

Exocrine Pancreatic Cancer

What is this study about?

The PATAKESS study is a research project focused on exocrine pancreatic cancer. This type of cancer is known to be very aggressive and one of the deadliest forms of cancer. Unfortunately, it often spreads early, making it difficult to treat effectively. While some newer treatments haven't shown much success for most pancreatic cancers, scientists are constantly looking for new ways to improve patient outcomes.

This study is unique because it's not trying out a new medicine or treatment. Instead, it's carefully looking at information and tissue samples that were already collected from patients who had surgery for pancreatic cancer at a hospital in France since January 2010. By examining these existing samples, researchers hope to find connections between the biological features of the tumours and the patients' health journeys. They want to understand how the cancer cells interact with the surrounding supportive tissue (called stroma) and what genetic changes might be present.

Learning more about these connections is really important. Even though much is known about pancreatic cancer from animal studies, there's still a lot to uncover about how it behaves in humans, especially concerning how tumours spread and react to treatments. By gathering this detailed information, the PATAKESS study aims to give scientists a better understanding of this complex disease, which could pave the way for developing more effective treatments and ultimately help improve the lives of people with pancreatic cancer.

Key takeaways

Researches exocrine pancreatic cancer using existing data.
Uses samples and records from patients treated since 2010 in France.
Aims to link tumour biology with patient outcomes.
Not a trial for new treatments, no active patient participation required.
Hopes to find clues for better future treatments.
Data privacy is strictly maintained.

Who may be eligible?

To be part of the PATAKESS study, you would have needed to be an adult, 18 years or older, who had surgery for exocrine pancreatic cancer at the Centre Léon Bérard hospital in Lyon, France, anytime from January 1, 2010, onwards.

Crucially, the diagnosis of exocrine pancreatic cancer must have been officially confirmed by looking at your surgical tissue sample. The study is reviewing existing patient information and stored tissue samples, rather than enrolling new patients for a new treatment.

Essentially, if you meet these specific conditions of having had your surgery and diagnosis at that particular hospital within the specified timeframe, your past medical information and tissue samples might be included in this research.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

Were you 18 years old or older at the time of your surgery?
Did you have surgery for exocrine pancreatic cancer?
Was your surgery performed at the Centre Léon Bérard hospital in Lyon, France?
Did your surgery happen on or after January 1, 2010?
Was your diagnosis of exocrine pancreatic cancer confirmed by a tissue sample?

Answer every question to see your result.

What does participation involve?

Since this is a study that looks at information and samples already collected, patients don't need to do anything extra. There are no special visits, tests, or medications involved for people whose data is being reviewed. Your participation would involve researchers using your existing medical records and tissue samples that were collected as part of your routine care when you had surgery. Therefore, there's no additional time commitment or follow-up required from you.

Potential risks and benefits

Because this study is using information and samples already collected from past medical care, there are no direct physical risks for individuals. Your personal information would be handled with strict privacy. The potential benefit is that this research helps scientists better understand pancreatic cancer, which could lead to improved diagnosis and treatment for future patients. You have the right to request that your de-identified data and samples not be used, if that option is available and communicated by the research site.

Locations (1)

Centre Léon Bérard
Verified postcode
Lyon, France· Recruiting

Common questions

What kind of cancer is this study about?

This study is focused on exocrine pancreatic cancer, which is a serious and often aggressive type of cancer.

Am I being asked to take part in a new treatment?

No, this is not a study testing new treatments. Researchers are looking at existing information and tissue samples from patients who have already had treatment.

Where is this study taking place?

The study is based on samples and data from patients treated at the Centre Léon Bérard hospital in Lyon, France.

What is the main goal of this research?

The main goal is to understand how the biological features of pancreatic tumours relate to how the disease progressed in patients, hoping to find better ways to treat it in the future.

Do I need to do anything if my information is used?

No, because the study uses pre-existing data and samples, you do not need to do anything extra or attend any appointments.

How to find out more

Philippe CASSIER

philippe.cassier@lyon.unicancer.fr 04 26 55 68 33 Official trial record

Always speak to your GP or specialist before deciding to take part in a study.