Not yet recruitingOBSERVATIONAL

Correlation of Urinary and Serum Hormone Levels in Natural Cycle Frozen Embryo Transfer Cycles

This research is investigating a new way to monitor hormone levels for women undergoing a "natural cycle frozen embryo transfer" (FET). This is a treatment for fertility issues. Usually, women need regular blood tests at a clinic to check their hormone levels. This study is testing if a home device, which measures hormones in urine, works just as well. The goal is to see if this home test can accurately predict the best time for the embryo transfer, potentially reducing clinic visits. If successful, it could make the FET process more convenient and less stressful for patients, saving them time and possibly money. It would also lead to a less invasive way to manage fertility treatment.

At a glance

Status

Not yet recruiting

Sponsor

Ottawa Fertility Centre

Enrolment target

100

Start

01 Jun 2024

Estimated completion

01 Dec 2025

Fertility Issues

What is this study about?

This study is for women who are having treatment for fertility issues, specifically a type called a "natural cycle frozen embryo transfer" (FET). During this treatment, it's very important to know exactly when your body is naturally ready for the embryo to be transferred. Currently, this usually means having several blood tests at a clinic to measure hormone levels, which can be time-consuming and sometimes stressful if you live far from the clinic.

Researchers want to find out if there's an easier way to do this. They are testing a special home device, similar to a home pregnancy test, but this one measures different hormones in your urine. These hormones, like estrone glucuronide (E3G) and luteinizing hormone (LH), tell doctors what's happening with your cycle and when you're about to ovulate (release an egg). The main question is whether the information from this home urine test matches the information from the regular blood tests.

The idea is that if the home test works well, you might be able to monitor your hormone levels at home instead of going to the clinic for blood tests as often. This could make the whole frozen embryo transfer process much more convenient, saving you time and money, and making your treatment journey a bit easier. It could also mean fewer needles and less disruption to your daily life if you know when your body is ready from home.

Key takeaways

This study explores a home urine test for natural cycle frozen embryo transfers.
It aims to reduce clinic visits and make treatment more convenient.
Compares home urine hormone levels to standard blood tests.
Could lead to a less invasive fertility treatment process.
Participation involves using a home device during your planned treatment.

Who may be eligible?

This study is looking for women who are already planning to have a natural cycle frozen embryo transfer. You would need to be able to understand the study information and agree to take part.

There are no specific reasons why you might not be able to join this study, as long as you meet the main criteria of having a natural cycle frozen embryo transfer planned and being willing to participate.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

Are you planning to have a natural cycle frozen embryo transfer?
Are you able to understand the study details?
Are you willing to use a home urine testing device?
Are you comfortable with your information being used for research?

Answer every question to see your result.

What does participation involve?

If you decide to take part in this study, you would be using a special home device called Mira. You would use this device to test your urine at home to measure your hormone levels, just as you normally would with your regular clinic appointments and blood tests. Researchers would then compare the results from your home tests with the results from your usual blood tests.

The study would take place during your existing natural cycle frozen embryo transfer cycle. There would be no extra clinic visits beyond what you would already be doing for your treatment. The study simply involves adding the use of the home testing device and allowing researchers to compare these results with your standard care. The total duration would be for one cycle of your frozen embryo transfer process.

Potential risks and benefits

A potential benefit of taking part in this study is contributing to research that could make fertility treatment simpler and more convenient for many women in the future, by potentially reducing the number of clinic visits and blood tests. There are no known direct medical risks from using the home urine testing device; it is a non-invasive tool. Your standard fertility care would continue as usual. You are free to withdraw from the study at any time without affecting your medical care.

Locations (1)

Olive Fertility Centre
Verified postcode
Vancouver, Canada

Common questions

What is a 'natural cycle frozen embryo transfer'?

It's a fertility treatment where a previously frozen embryo is placed into your womb during your natural menstrual cycle, without using extra hormones to prepare your body.

What is the 'Mira device'?

It's a home device that measures hormone levels in your urine, similar to how a home pregnancy test works, but it gives more detailed information about your cycle.

Will I still have blood tests if I join this study?

Yes, you will continue with your standard blood tests as part of your fertility treatment. The study is comparing the home test results with your regular blood test results.

Will using this device affect my chances of getting pregnant?

No, using the device won't affect your chances. Your doctor will still manage your treatment based on existing medical guidelines.

Do I have to pay to use the home device?

The study information doesn't specify. You should ask the research team if there are any costs associated with using the Mira device for the study.

How to find out more

Jennifer McDowall

jmcdowall@conceive.ca 613-686-3378 Official trial record

Always speak to your GP or specialist before deciding to take part in a study.