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RecruitingNAINTERVENTIONAL

The Value of Advanced Imaging Sequences for Fetal MRI in Clinical Practice

Doctors sometimes use MRI scans to get detailed pictures of unborn babies when there are concerns about their health. This study aims to make these MRI scans even better. We're looking at four main things: firstly, if new scanning methods can give clearer, more helpful images; secondly, if using a stronger MRI machine (called 3T) improves the pictures compared to the standard one (1.5T); thirdly, if we can use MRI to see the baby's heart more clearly; and fourthly, if we can use it to get better images of the baby's bones. The goal is to help doctors get the best possible information to guide care.

At a glance

Status
Recruiting
Phase
NA
Sponsor
Sheffield Teaching Hospitals NHS Foundation Trust
Enrolment target
150
Start
01 Aug 2013
Estimated completion
31 Dec 2025

What is this study about?

When doctors have concerns about an unborn baby's health, they sometimes recommend an MRI scan to get detailed pictures. These scans help them understand the baby's condition better. However, the way these scans are done, including the specific settings and techniques used (doctors call these "sequences"), hasn't changed much, and there's always room for improvement. This study is all about finding new and better ways to perform these MRI scans.

We're exploring several key areas. We want to know if different scanning techniques, which might highlight specific parts of the baby's body more clearly, could give doctors more useful information. Imagine trying to take a picture of something inside a dark room – different camera settings could make the image much clearer. We're also investigating whether using a stronger MRI machine (called a 3 Tesla or 3T scanner, compared to the standard 1.5 Tesla or 1.5T) makes a significant difference to the quality and usefulness of the images. Recently, using these stronger machines for pregnant women has been allowed in the UK, but we need to understand their full benefits.

Finally, we're looking into whether MRI can be reliably used to get good pictures of parts of the baby's body that are currently hard to see clearly, such as the heart and bones. If we can get better images of these areas, it could greatly help doctors diagnose problems earlier and plan the best care for the baby. This study is a first step, or 'pilot study,' to evaluate these new methods and see if they could eventually become part of routine hospital care.

Key takeaways

  • A research study exploring ways to improve MRI scans for unborn babies.
  • Investigating new scanning techniques for clearer images of organs like the heart and bones.
  • Comparing standard MRI machines (1.5T) with stronger ones (3T) for better picture quality.
  • Aims to provide doctors with more detailed information to help manage a baby's health.
  • Participation involves an MRI scan with no additional medications.
  • Your medical care will not be affected regardless of participation.

Who may be eligible?

You might be able to take part in this study if you are pregnant and your doctor has suggested an MRI scan because there are concerns about your baby's health, and this scan would help guide your care. You would also be asked to consider an MRI scan using a 3T scanner.

Another group who might be eligible are pregnant women who have decided to end their pregnancy and agree to have an MRI scan using a 3T machine before the procedure. This is because the scans could provide valuable research information.

You would not be able to take part if you have anything that would make an MRI scan unsafe for you (like certain metal implants) or if you experience severe claustrophobia, which is a strong fear of confined spaces, as MRI scanners are enclosed.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

  1. Are you pregnant and considering an MRI scan for your baby's health?
  2. Or are you pregnant and planning to end your pregnancy, willing to have an MRI before?
  3. Do you have any metal implants or devices that make MRI unsafe for you?
  4. Do you experience severe claustrophobia (a strong fear of confined spaces)?
Answer every question to see your result.

What does participation involve?

If you decide to take part, you would have an MRI scan. This scan would be similar to regular MRI scans but would use a stronger 3T machine and include some new scanning techniques that the researchers are testing. Having an MRI scan usually involves lying still for a period inside a large, tube-shaped machine. The total duration of the scan itself, including the new techniques, would be carefully managed to ensure it's not too long. There are no extra hospital visits beyond what would normally be expected for your antenatal care and MRI.

Potential risks and benefits

Taking part might offer the benefit of potentially contributing to medical knowledge that could improve future care for other unborn babies. While there are no direct personal benefits from testing the new techniques, your scan will still provide information to your care team as standard. MRI scans are generally considered safe for pregnant women, but as with any medical procedure, there are minor risks that your doctor will discuss with you. These include the discomfort of lying still in an enclosed space. You are completely free to withdraw from the study at any time without affecting your medical care.

Locations (1)

Some site locations are approximate. We're improving this — please verify with the trial team before travelling.
  • Sheffield Teaching Hospital NHS Foundation Trust
    Verified postcode
    Sheffield, United Kingdom· Recruiting

Common questions

What is an MRI scan?

An MRI (Magnetic Resonance Imaging) scan uses strong magnets and radio waves to create detailed pictures of the inside of your body, including your unborn baby.

Why are you looking at new scanning methods?

We want to find ways to get clearer, more informative pictures of unborn babies to help doctors understand and respond to any health concerns better.

What is a 3T MRI machine?

A 3T MRI machine is a stronger type of scanner compared to the standard 1.5T. We're investigating if this stronger machine provides better quality images for babies.

Will this study affect my baby's care?

No, your participation will not negatively affect your baby's care. The scan will provide information for your care team, and the research aspect aims to improve future care for others.

Is an MRI scan safe for my baby?

MRI scans are considered safe for unborn babies. They don't involve X-rays or radiation. Your medical team can discuss any concerns you have.

How to find out more

Elspeth Whitby

Always speak to your GP or specialist before deciding to take part in a study.

Interested in taking part?

Register your interest

Share your details and the research team for "The Value of Advanced Imaging Sequences for Fetal MRI in Cli…" will contact you if you may be eligible. Always speak to your GP before agreeing to take part.

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