Examining heart and blood vessel health in women with a history of high blood pressure during pregnancy using ultrasound and eye scans
This study is investigating heart and blood vessel health in women. Specifically, it focuses on those who experienced high blood pressure during pregnancy, as they may be at higher risk of heart problems later in life compared to women who had normal blood pressure during pregnancy. Researchers will use simple and painless methods like special eye and neck scans (ultrasound) to examine tiny blood vessels. They will also take a blood sample. The goal is to see if these quick tests can help doctors understand who might develop heart conditions in the future. There are no direct benefits for participants, but the information gained will help improve care for pregnant women in the future by allowing for earlier detection of potential health issues.
At a glance
What is this study about?
When a woman has high blood pressure during pregnancy, it’s a condition that can affect about 1 in 10 pregnancies. While many women recover fully, research shows that having high blood pressure during pregnancy can increase the chance of developing heart and blood vessel problems later in life. This study aims to understand this link better and find ways to identify women who might be at a higher risk.
The research team wants to explore if new and easy methods can help tell us about the health of your blood vessels. They will use a special camera to take photos of the back of your eye, and also use ultrasound scans on your eye and neck, similar to scans given during pregnancy. They will also take a small blood sample. These tests are chosen because they can show changes in tiny blood vessels, which are important for managing blood pressure.
By comparing women who had high blood pressure during pregnancy with those who didn't, the researchers hope to discover if these simple tests can become a useful tool for doctors. The ultimate goal is to improve how we care for women after pregnancy, helping to spot potential health issues earlier so they can be managed effectively.
Key takeaways
- Looks at heart and blood vessel health after pregnancy.
- Focuses on women who had high blood pressure during pregnancy.
- Uses simple tests: eye photos, eye and neck ultrasounds, and a blood test.
- Aims to find ways to identify future heart risks sooner.
- No direct benefit to participants, but helps future pregnant women.
- Study takes place at Ninewells Hospital, Dundee.
Who may be eligible?
This study is looking for women aged 18 or over.
You can take part if you had your last baby between 6 months and 5 years ago. We are specifically looking for women who either had normal blood pressure during their last pregnancy or women who had high blood pressure (also known as gestational hypertension) during their last pregnancy.
However, you cannot take part if you had high blood pressure before you were pregnant, have certain eye conditions, or are already involved in another clinical trial that affects your health.
Could this study suit you?
Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.
- Are you 18 years old or older?
- Did you give birth between 6 months and 5 years ago?
- Did you have normal blood pressure during your last pregnancy, OR did you have high blood pressure (gestational hypertension) during your last pregnancy?
- Do you NOT have high blood pressure that started *before* pregnancy?
- Do you NOT have certain eye conditions?
What does participation involve?
If you decide to take part, you will visit Ninewells Hospital in Dundee. The study involves a few simple and generally quick tests. You will have a photograph taken of the back of your eye, which is similar to what an optician does. You will also have ultrasound scans of your eye (with your eye closed) and your neck. These ultrasounds are painless and use sound waves to look at your blood vessels. Finally, a small blood sample will be taken from your arm, much like a routine blood test you might have at your GP surgery. All these assessments happen during a single visit. The study is expected to run from October 2023 to June 2026.
Potential risks and benefits
Locations (1)
- Ninewells HospitalApproximateDundee, Scotland
Common questions
What is high blood pressure during pregnancy?
It's when your blood pressure is higher than normal *only* when you are pregnant. It usually goes back to normal after the baby is born.
Is the eye photography painful?
No, it's not painful. It's like having a quick photo taken at the optician’s, and your eye will be open for it.
Will I get my test results?
This study is for research, so you won't automatically get individual results. However, the overall findings will help improve future care.
How long will the appointment take?
The information doesn't specify the exact duration, but all assessments will be done in one visit.
Where is the study taking place?
The study is being run from Ninewells Hospital in Dundee, Scotland.
How to find out more
Sarah Alkhurainej
Always speak to your GP or specialist before deciding to take part in a study.
Discussion
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