Does the LINX procedure achieve similar reflux control and improve postoperative symptoms, specifically gas bloating and inability to belch, when compared to laparoscopic fundoplication?

You may be able to join this study if you are 18 or older and have severe acid reflux (GORD) that is not well managed by medicines, or if you cannot tolerate reflux medications. Your reflux must be confirmed through routine hospital tests, such as an endoscopy (a small camera looking down your food pipe) or a 24-hour acid level test. You will also need to have good muscle movement in your food pipe and no large hiatus hernia.

You will not be eligible if you have already had surgery on your stomach or food pipe, or if you have medical conditions that make general anaesthetics unsafe. Because the LINX device contains metal magnets, people with known metal allergies (such as nickel or titanium) or those who have had or need brain or nerve surgery cannot take part.

Taking part in the GOLF study lasts for around two years in total. If you take part, a computer will randomly assign you to have either standard fundoplication surgery or the LINX magnetic ring procedure. Both are performed as keyhole operations under general anaesthetic, meaning you will be asleep throughout. Neither you nor your research team can choose which operation you receive.

After your operation, the research team will check on your recovery at regular intervals: 6 weeks, 6 months, 12 months, and 24 months. During these follow-up checks, you will answer questions about your symptoms, your general quality of life, and whether you experience bloating or swallowing difficulties. You may also have follow-up tests to measure acid levels in your food pipe so doctors can see how well your operation is working.