CompletedNot ApplicableInterventional

Root canal treatment outcomes using different ways to clean and disinfect teeth, including light technology (LASER)

This study is investigating different ways to clean and disinfect the inside of teeth during a common dental procedure called root canal treatment. The main goal is to find out if using special methods, including light technology (laser) or sonic vibrations, can help improve the success of root canal treatments for infected teeth. If successful, these new methods could lead to better outcomes for patients needing this treatment in the future. Participants will undergo root canal treatment, with a specific part of the cleaning process being varied between groups. The study also involves follow-up appointments over two years to check on the treatment's success. It aims to develop a better understanding of how to achieve the best possible results for patients.

At a glance

Status

Completed

Phase

Not Applicable

Sponsor

University of Central Lancashire

Enrolment target

264

Start

10 Jan 2023

Estimated completion

31 May 2025

Healing of apical periodontitis (due to primary endodontic infection)

What is this study about?

When a tooth gets infected inside, a common treatment is a root canal. This involves cleaning out the infection and sealing the tooth. This study wants to find out if different ways of cleaning and disinfecting the inside of the tooth during a root canal can make the treatment work better in the long run. We're looking at special tools that use sound waves (sonic) or light (laser) to help clean more thoroughly.

Imagine your tooth has tiny, intricate pipes inside. This study is testing if using these special tools to activate the cleaning liquid in those pipes makes the tooth much cleaner than just using a simple hand-swishing method. By doing this, we hope to improve how well the root canal treatment heals the infection and saves the tooth.

This research is important because if we find a better way to clean teeth during root canals, it could mean more successful treatments for many people in the future. We want to make sure people get the best possible outcome when they need a root canal.

Key takeaways

This study compares different cleaning methods for root canal treatment.
It aims to find out if new techniques, including laser, can improve success.
Participants will have standard root canal treatment with one modified step.
There are 5 appointments over two years, including follow-ups.
No extra risks beyond usual root canal treatment.
Your participation could help improve future dental care for others.

Who may be eligible?

This study is looking for adults aged 18 or over who are generally healthy and need a root canal treatment for an infected tooth. This includes any tooth, whether it's at the front or back of your mouth.

However, there are some reasons why you wouldn't be able to join. For example, if you're pregnant, have certain conditions like 'root resorption' (where your tooth root is being dissolved), or if you've recently taken antibiotics. Also, if you have a weakened immune system, you wouldn't be able to take part.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

Are you 18 years or older?
Do you need a root canal treatment for an infected tooth?
Are you generally in good health?
Are you NOT pregnant?
Have you NOT taken antibiotics in the last month?
Do you NOT have a weakened immune system?

Answer every question to see your result.

What does participation involve?

If you decide to take part, you'll have your root canal treatment as planned, but one specific step in the cleaning process will be part of the study. This involves using a special method to activate the cleaning liquid inside your tooth for about 1 to 2 minutes per root canal. You'll be randomly put into one of three groups, each receiving a different method: manual cleaning, sonic cleaning, or laser cleaning.

You'll need to attend five appointments in total: an initial visit for assessment and consent, the treatment itself, and then check-ups after 2 weeks, 1 year, and 2 years. Your information will be kept private, with details about your treatment and X-rays shared only in an anonymous way with researchers at the University of Central Lancashire for analysis. You can choose to leave the study at any time without it affecting your care.

Potential risks and benefits

There are no extra risks involved in taking part in this study beyond those already associated with standard root canal treatment. While there's no direct personal benefit to you for participating, your involvement will help us learn more and potentially improve future root canal treatments for other patients. You are free to withdraw from the study at any time without needing to give a reason, and this will not affect the quality of care you receive.

Locations (3)

University of Central Lancashire
Approximate
Preston, United Kingdom
Dawood and Tanner Specialist Dental Practice
City only
London, United Kingdom
Colchester Dental Specialist Clinic
City only
Colchester, United Kingdom

Common questions

What is a root canal treatment?

It's a common dental procedure to remove infection from inside a tooth, clean it, and seal it to save the tooth.

What does 'sonic activation' mean?

It's a method that uses sound waves to help clean the inside of the tooth more thoroughly during a root canal.

Will I know which cleaning method I receive?

You will be randomly assigned to one of the three cleaning methods, but the research team will inform you of your specific treatment outcomes.

How long will the study last for me?

You will have five appointments over a two-year period: an initial visit, treatment, and follow-ups at 2 weeks, 1 year, and 2 years.

What happens if my root canal treatment doesn't work?

If your treatment isn't successful, the research team will provide the standard follow-up care, such as repeating the root canal, removing the tooth, or other necessary treatments.

How to find out more

Shalini Kanagasingam

skanagasingam1@uclan.ac.uk +44 7398276670 Official trial record

Always speak to your GP or specialist before deciding to take part in a study.