A study in healthy people to test whether BI 764198 influences the amount of metformin in the body
This is an early-stage research study, sometimes called a Phase I trial. We are inviting healthy volunteers to take part. The main goal is to find out if a new investigational medicine, called BI 764198, affects how the body handles metformin. Metformin is a widely used drug for managing type 2 diabetes. By understanding how these two medicines interact, if at all, we can ensure future treatments are developed safely and effectively. You won't receive BI 764198 on its own; the focus is on its interaction when taken with metformin. This type of study is crucial for learning about new medicines before they are tested in people who are unwell. Participation helps advance medical knowledge for everyone.
At a glance
What is this study about?
This research study is one of the very first steps in testing a new medicine called BI 764198. It's called a 'Human Pharmacology' study, which means we are studying how the medicine works in the human body. The main purpose of this study is to carefully look at whether BI 764198 changes how much of a common diabetes medicine, called metformin, stays in your body.
Metformin is a well-known drug that many people take to help manage their blood sugar levels. If a new medicine is going to be used alongside metformin in the future, it's really important to know if they affect each other. This study aims to gather this vital information, helping researchers understand any potential interactions and making sure that any future treatments involving BI 764198 are as safe and effective as possible.
By taking part, you would be helping medical science. This kind of early research in healthy people is essential before new medicines can be tested further in patients who might eventually benefit from them. It's all about making sure new treatments are developed thoughtfully and with safety as a top priority.
Key takeaways
- This study is for healthy volunteers.
- It's exploring how a new medicine (BI 764198) interacts with metformin (a diabetes drug).
- It's an early-stage study to gather safety information.
- You must be 18 years or older to participate.
- Participation helps advance medical research.
Who may be eligible?
This study is looking for healthy adults. You need to be at least 18 years old to take part, and there's no upper age limit, as long as you are generally healthy.
Both men and women are welcome to participate in this research. The most important thing is that you consider yourself to be in good health. A medical team will check your health carefully to ensure it's safe for you to join some medical trials.
- Are you at least 18 years old?
- Do you consider yourself to be in good health?
- Do you currently have any serious ongoing medical conditions?
- Are you willing to take study medication and attend clinic visits?
This is a guide only — the research team will confirm whether you can take part.
What does participation involve?
Details about what taking part involves are not fully available in the brief summary. However, in studies like this, participants typically undergo an initial screening visit to check their health. If eligible, you would likely have several visits to a clinic over a period of days or weeks. These visits often include blood tests, urine tests, and monitoring of your vital signs (like blood pressure and heart rate). You would be given the study medication (BI 764198 alongside metformin) and observed closely. There would also be follow-up appointments after you stop taking the medicine to ensure you are well. The total duration of the study would be explained to you before you agree to take part.
Potential risks and benefits
Locations (1)
- —Germany
Common questions
What does 'healthy volunteer' mean?
It means you don't have any significant ongoing health conditions or take regular medications that could affect the study results, and you are generally well.
What is metformin?
Metformin is a common medication used to treat type 2 diabetes, helping people control their blood sugar levels.
Will I be given the new medicine (BI 764198) alone?
No, this study specifically looks at how BI 764198 interacts with metformin, so you would receive both.
What is a Phase I study?
Phase I is an early stage of clinical research, usually done in a small group of healthy people, to check if a new medicine is safe and how it behaves in the body.
Will I get paid for taking part?
Clinical trials often offer payment for your time and expenses, but this will be confirmed when you inquire about the study.
How to find out more
Always speak to your GP or specialist before deciding to take part in a study.
Discussion
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