AuthorisedHuman Pharmacology (Phase I)- OtherInterventional

A study in healthy people or otherwise healthy but overweight or obese to compare 2 formulations of survodutide given in different ways, either as a pre-filled syringe or a pen-like injector

This research study is for healthy adults, including those who are overweight or have obesity. It's designed to compare two different ways of giving a medicine called survodutide. Participants will either receive the medicine using a pre-filled syringe (a single-use injection) or a pen-like injector, which is often used for medicines given at home. The main goal is to understand how the medicine behaves in the body when given by these two different devices. This is an early-stage study, meaning it's one of the first times this medicine is being tested in people. It helps scientists learn more about how to best give new medicines before they are tested in larger groups of people with specific health conditions.

At a glance

Status

Authorised

Phase

Human Pharmacology (Phase I)- Other

Sponsor

Boehringer Ingelheim International GmbH

Enrolment target

Start

28 Apr 2026

Healthy volunteer trial

What is this study about?

Imagine you have a new and important ingredient for a cake, but you're not sure if it's best to add it with a spoon or a measuring cup. This study is a bit like that, but for a new medicine called survodutide. Researchers want to find out the best way to give this medicine to people. They are comparing two common ways to inject medicine: a pre-filled syringe, which is a single-use injection, and a pen-like injector, which might be easier for people to use at home.

This study is for healthy volunteers, which means people who don't have any major health problems. It also includes people who are overweight or have obesity. By studying healthy individuals, researchers can understand how the medicine works in the body without other health conditions making things complicated. This helps them get a clear picture of how survodutide is handled by the body when given by each device.

This is an early phase study, sometimes called a Phase I study. These studies are very important because they help researchers understand how safe a medicine is and how the body processes it. The information gathered here will help decide how to best use survodutide in future, larger studies, especially if it proves useful for treating certain health conditions later on. It’s a key step in developing new medicines.

Key takeaways

This study compares two ways of giving a new medicine called survodutide.
It's for healthy adults, including those who are overweight or have obesity.
The goal is to understand how the medicine works in the body and which delivery method is better.
This is an early-stage study (Phase I) focused on safety and how the body handles the medicine.
Your participation helps advance medical research.

Who may be eligible?

To join this study, you need to be a healthy adult aged 18 or older. This means you generally don't have any serious ongoing health problems.

Even if you are considered overweight or have obesity, you can still participate, as long as you are otherwise healthy. Both men and women are welcome to take part in this research.

If you have any serious medical conditions that require ongoing treatment, you would likely not be able to join this particular study.

Quick self-check

Are you 18 years old or older?
Do you consider yourself generally healthy?
Are you possibly overweight or do you have obesity, but no other major health issues?
Are you able to commit to several appointments at a study clinic?

This is a guide only — the research team will confirm whether you can take part.

What does participation involve?

If you decide to take part, you will be given the study medicine, survodutide, either through a pre-filled syringe or a pen injector. You will likely have several visits to a clinic or research centre. During these visits, the research team will monitor your health, take blood samples, and ask you questions about how you are feeling to see how the medicine is affecting you. They will also check your vital signs like blood pressure and heart rate. The exact number of visits and the total length of time you'll be involved will be explained in detail before you agree to participate.

Potential risks and benefits

Potential benefits of taking part could include contributing to medical science and helping to develop new medicines. You may not personally benefit from taking part. Like all medicines and medical procedures, there are potential risks, such as side effects from the study medicine or discomfort from blood tests and injections. These will be fully explained to you before you decide to join. You have the right to withdraw from the study at any time, for any reason, without it affecting your medical care.

Locations (1)

—
Germany

Common questions

What is survodutide?

Survodutide is the name of the medicine being tested in this study. It's a new medicine that researchers are learning about.

Why are you looking at two different ways to give the medicine?

Researchers want to find the best and most comfortable way for people to receive this medicine, whether that's with a simple syringe or a pen-like device.

Will this medicine help me with my weight?

This study is mainly about how the body handles the medicine and the best way to give it. It's not specifically designed to treat weight or other conditions at this stage. It's an early safety and dosage study.

Do I need to do anything special before joining?

You will have a health check-up to make sure you are healthy enough for the study. Specific instructions will be given to you by the study team.

Will I get paid for taking part?

Some studies offer payment for your time and travel, but this varies. The study team will tell you if this is the case for this particular study.