Ongoing, recruitingHuman Pharmacology (Phase I)- OtherInterventional

Oral vs Intravenous Fluids – healthy volunteers

This research study is for healthy volunteers and aims to understand how your body reacts to different ways of receiving fluids. Doctors want to compare what happens in your body when you drink fluids normally versus when fluids are given through a drip into your vein. This is an early-stage study, often called Phase 1, which focuses on learning more about how the body works. It's not testing a new medicine or treatment, but rather trying to understand how various methods of fluid intake affect important body measurements like blood pressure and heart rate. This information can help doctors make better decisions about giving fluids in the future.

At a glance

Status

Ongoing, recruiting

Phase

Human Pharmacology (Phase I)- Other

Sponsor

Esbjerg Og Grindsted Sygehus

Enrolment target

Start

26 Feb 2025

Hemodynamic parameters is to be investigated -- comparing intravenous fluid therapy to oral fluid therapy

What is this study about?

Imagine you're feeling a bit dehydrated. There are two main ways to get fluids into your body: by drinking them or, if you're very unwell, by having them given intravenously (through a drip into a vein). This study wants to compare these two methods in healthy adults. It's like a scientific experiment to see how your body handles fluids differently depending on how they enter your system.

The main thing researchers are looking at is something called 'hemodynamic parameters'. Don't worry about the big word! It simply means they'll be checking things like your blood pressure, heart rate, and how well blood is flowing around your body. By comparing these measurements when you receive fluids orally (by mouth) versus intravenously (through a drip), they hope to learn more about how your body controls and circulates fluids.

This kind of study is really important because it helps doctors understand the basics of how our bodies work. The information gathered here could, in the long run, help them make better decisions about the best way to give fluids to patients in different situations, whether it's during an illness, after surgery, or in other medical scenarios.

Key takeaways

This study compares drinking fluids to having them given through a drip.
It's for healthy adults aged 18 and over.
Researchers will measure things like blood pressure and heart rate.
The goal is to understand how the body handles different ways of receiving fluids.
Your participation helps to improve general medical knowledge.
You can withdraw from the study at any time without consequences.

Who may be eligible?

To take part in this study, you need to be a healthy adult.

There isn't a strict upper age limit, but you must be at least 18 years old. Both men and women can join the study.

The researchers are specifically looking for people who are generally well and don't have any major ongoing health conditions. This is because they want to understand how fluids affect a typical healthy body, without other health issues complicating the results.

Quick self-check

Are you 18 years old or older?
Are you generally healthy with no major ongoing medical conditions?
Are you comfortable with possibly having an intravenous drip inserted?
Are you able to attend study visits as required?

This is a guide only — the research team will confirm whether you can take part.

What does participation involve?

The detailed steps for taking part aren't fully described, but based on similar studies, you might expect:

* **Initial Check-up**: Before you start, you'll likely have a health check to make sure you're suitable for the study. * **Study Visits**: You'll probably need to attend a clinic or hospital for scheduled visits. These visits might involve having blood pressure and heart rate taken regularly. * **Fluid Administration**: During these visits, you'll either be given fluids to drink (oral fluid therapy) or fluids through a drip into your arm (intravenous fluid therapy). These will be done at different times so researchers can compare the effects. * **Assessments**: Throughout the study, medical staff will monitor various body measurements, likely including heart rate, blood pressure, and possibly other tests to see how your body is responding. * **Duration**: The total duration of your participation, including how many visits and how long each lasts, would be explained in full detail by the research team.

Potential risks and benefits

Participating in research always has a balance of potential benefits and risks. A potential benefit of taking part is contributing to medical knowledge that could help future patients. You might also receive a thorough health check-up during the screening process. Potential risks could include minor discomfort from blood pressure cuffs or having a drip inserted, as well as the time commitment involved. You always have the right to withdraw from the study at any time, for any reason, without it affecting your usual medical care.

Locations (1)

—
Denmark

Common questions

What does 'hemodynamic parameters' mean in simple terms?

It simply refers to how your blood is flowing through your body, including things like your blood pressure and heart rate.

Will I be given any new or experimental drugs?

No, this study is about common ways of giving fluids (drinking or through a drip), not new medications.

Is this study meant to treat a specific illness?

No, this is a basic research study to understand how healthy bodies handle fluids. It's not a treatment for any condition.

Do I have to stay in hospital for this study?

The full details are not specified, but for studies like this, you might attend outpatient visits rather than staying in hospital, though some monitoring periods could be longer.

What's the main goal of this research?

The main goal is to understand how your body reacts differently when you drink fluids compared to receiving them through a drip, to help doctors make better decisions about fluid management in the future.