AuthorisedTherapeutic use (Phase IV)Interventional

PREDICTION OF COMPLICATIONS IN PATIENTS UNDERGOING SURGICAL TREATMENT OF HEPATIC TUMORS

This research is investigating new methods to predict potential complications for patients undergoing surgery for liver tumours. The main goal is to compare a special imaging test, called Tc-99m GSA SPECT/CT, with existing liver function tests. Researchers want to see if this scan can more accurately predict who might experience significant problems after surgery. By doing this, doctors hope to get a clearer picture of a patient's liver health before an operation, allowing them to better prepare and potentially improve recovery outcomes. The study also looks at how these tests relate to things like how long patients stay in hospital and their general recovery.

At a glance

Status

Authorised

Phase

Therapeutic use (Phase IV)

Sponsor

Rigshospitalet

Enrolment target

192

Start

17 Mar 2026

Hepatic tumor Hepatic tumor(s)

What is this study about?

If you need surgery for a liver tumour, your doctors will carry out tests to check how healthy your liver is. This helps them understand how well you might recover after the operation. This study is looking at new ways to predict problems that could happen after this type of surgery.

Researchers are using a special type of scan called Tc-99m GSA SPECT/CT. They want to see if this scan can give doctors a better idea of your liver health and predict any major issues after surgery, compared to the standard tests currently used. They're also checking how this scan compares to other measures like the Child-Pugh and MELD scores, which are common ways doctors assess liver health.

The ultimate aim is to find the most accurate way to understand your risk of complications before surgery. This could allow doctors to make more informed decisions about your treatment plan, hopefully leading to better and safer outcomes for patients undergoing liver tumour surgery.

Key takeaways

This study is about improving predictions for liver surgery recovery.
It compares a new scan with standard liver tests.
The goal is to reduce complications after liver tumour surgery.
Participation involves extra scans and follow-up, not new medicines.
It aims to help doctors better understand your liver health before surgery.

Who may be eligible?

This study is looking for both men and women to take part. To be considered, you need to be at least 18 years old. There's no upper age limit mentioned.

You would be considered if you are currently planning to have surgery for a liver tumour. The study is particularly interested in understanding how different tests can predict recovery after this specific type of operation.

If you have a liver tumour and are scheduled for surgery, and you meet the age requirements, your medical team can help determine if this study is suitable for you.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

Are you 18 years old or older?
Are you scheduled for surgery for a liver tumour?
Are you willing to have an extra scan (Tc-99m GSA SPECT/CT)?
Are you comfortable with being followed up for 90 days after surgery?

Answer every question to see your result.

What does participation involve?

If you decide to take part in this study, it would involve undergoing the special Tc-99m GSA SPECT/CT scan as well as standard liver function tests. Researchers will compare the results of these different tests. They will also collect information about your recovery after surgery, including how long you stay in hospital, any complications, and your general health in the 90 days following your operation. You won't be given any new medication as part of the study; it focuses on testing and observation. The total duration of your participation would involve the pre-surgery assessments, the surgery itself, and follow-up for 90 days afterwards.

Potential risks and benefits

Taking part in this study could help doctors better understand your liver health before surgery, potentially leading to more personalised care. While the Tc-99m GSA SPECT/CT scan involves a small amount of radiation, this is carefully monitored and considered to be a low risk. As with any medical procedure, there's always a slight chance of discomfort or an allergic reaction to the substances used in the scan, though these are rare. You have the right to withdraw from the study at any time without giving a reason, and this will not affect your medical care.

Locations (1)

Some site locations are approximate. We're improving this — please verify with the trial team before travelling.

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Unverified
Denmark

Common questions

What is a liver tumour?

A liver tumour is an abnormal growth of cells in your liver. It can be non-cancerous (benign) or cancerous (malignant).

What is the purpose of this study?

This study aims to find better ways to predict potential problems after surgery for liver tumours, using a special scan.

Will I receive a new medicine as part of this study?

No, this study is about comparing different tests and how they predict your recovery, not about giving new medicines.

Who can take part in this study?

Anyone aged 18 or over who is having surgery for a liver tumour may be eligible.

What does Tc-99m GSA SPECT/CT mean?

It's the name of a special imaging scan that helps doctors look at how well your liver is working.