Implementation of Out-of-HOspital administration of the Long-Acting combination cabotegravir+rilpivirine as an optional therapy in HIV-Infected patients from Spain. Acceptability, appropriateness, feasibility and satisfaction. The HOLA Study.

To assess and compare acceptability, we will use the Acceptability Intervention Measure (AIM) questionnaire - Number and proportion of participants receiving injections that show an average composite score ≥ 4 across the AIM questionnaires at month 12.- Differences among the proportion of participants receiving injections with an average composite score ≥ 4 across the AIM questionnaires at month 12- Average composite score across the AIM questionnaires at 12., To assess and compare the safety and tolerability of LA CAB+RPV: Incidence and severity of CAB + RPV LA–related AEs, all SAEs, ISRs or post injection reactions. % of participants who discontinue CAB + RPV LA due to AEs/SAEs at any time, and at m6&m12. Comparing between groups number and % of patients who withdraw treatment study at m6&m12 due to antiretroviral-related AE and reasons.Comparing between groups number and % patients whith grade 3 or 4 antiretroviral-related AEs at m6&m12.