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RecruitingNAINTERVENTIONAL

Eye Imaging for the Study of Childhood Myopia

Short-sightedness, also known as myopia, is becoming much more common, especially in children. In fact, experts think that by 2050, about half the world's population could be short-sighted. For some, it can lead to serious eye problems later in life. We have treatments to slow down short-sightedness in children, but they don't work the same for everyone. This study wants to find out why. Researchers believe that the unique shape and structure of a child's eye might affect how well a treatment works. By taking detailed pictures and measurements of children's eyes, this study aims to understand these differences better. The goal is to help doctors create more personalised and effective treatments for children with short-sightedness.

At a glance

Status
Recruiting
Phase
NA
Sponsor
Essilor International
Enrolment target
100
Start
18 Feb 2026
Estimated completion
01 Dec 2027

What is this study about?

Short-sightedness, or myopia, means that distant objects look blurry, while close-up objects appear clear. It's becoming a major concern globally, and it's particularly affecting children. This is worrying because severe short-sightedness can increase the risk of serious eye conditions later in life, such as a detached retina, or problems with the central part of the vision (macula) or the optic nerve (glaucoma).

While there are treatments available to help slow down the worsening of short-sightedness in children, they don't work equally well for all young patients. Scientists don't yet fully understand why some children respond better than others. One idea is that the specific shape and structure of a child's eye might play a role in how effective a particular treatment is for them.

This research, called "Eye imaging for the study of childhood myopia," aims to learn more about the detailed structure of children's eyes. By using advanced imaging techniques, like detailed scans and precise eye measurements, the researchers hope to uncover these differences. They will then analyse this information to get a better understanding of children's eye anatomy. The ultimate goal is to use this knowledge to develop more effective and personalised ways to manage short-sightedness in children, making sure each child gets the best possible treatment for their eyes.

Key takeaways

  • Short-sightedness (myopia) is increasing, especially in children.
  • Current treatments don't work for everyone, and we don't fully understand why.
  • This study uses eye scans and measurements to examine eye structure in children.
  • The goal is to understand differences in eye anatomy to improve future treatments.
  • It helps us move towards more personalised care for children with short-sightedness.

Who may be eligible?

This study is looking for children aged between 6 and 12 years old who are covered by social security in the UK. Their parents or legal guardians must give written permission for them to take part.

Children can't join if they have certain other health conditions. This includes if they have a diagnosed problem affecting their brain or nerves, like epilepsy or issues with balance. They also can't participate if they have other ongoing or worsening eye conditions apart from short-sightedness, such as glaucoma or problems with eye movement like a 'lazy eye' (strabismus) or uncontrolled eye wobbling (nystagmus).

Additionally, children who have had cataract surgery (meaning they have an artificial lens in their eye) or who cannot have an MRI scan (for example, due to claustrophobia or having certain metal implants like a pacemaker) will not be able to take part.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

  1. Is your child aged 6 to 12 years?
  2. Is your child covered by UK social security?
  3. Can both parents/guardians give written permission?
  4. Does your child have short-sightedness, but no other serious eye problems?
  5. Does your child have no nerve or brain disorders, e.g., epilepsy or balance issues?
  6. Is your child able to have an MRI scan (no claustrophobia or certain implants)?
Answer every question to see your result.

What does participation involve?

Taking part in this study would involve having various eye measurements and scans. This includes standard eye tests and special detailed images of the eye, possibly using an MRI scanner. The study is focused on gathering information about the eye's structure and doesn't involve new medications or treatments. There will be no follow-up treatment as part of this study, as it's purely for understanding eye anatomy. The total duration of participation will likely involve one or a few visits to complete all the necessary measurements and imaging. The researchers will be able to tell you exactly how many visits and how long each visit will be.

Potential risks and benefits

Participating in this study will help researchers gain valuable insights into childhood short-sightedness, which could lead to better treatments for many children in the future. There are no direct medical benefits to your child from taking part, as it's an observational study. The risks typically include minor discomfort from routine eye exams and lying still for imaging like an MRI scan. All procedures are carefully monitored. You and your child have the right to withdraw from the study at any time without explaining why, and this will not affect your child's medical care in any way.

Locations (1)

  • Hôpital Fondation Adolphe de Rothschild
    Verified postcode
    Paris, France· Recruiting

Common questions

What is short-sightedness (myopia)?

It's when distant objects look blurry, but close-up things are clear. It happens when the eye grows too long, or the front of the eye (cornea) is too curved.

Why is this study important for children?

Short-sightedness often gets worse as children grow. This study helps us understand why treatments work better for some children than others, aiming to find better ways to help them.

What kind of tests will my child have?

Your child will have standard eye checks and special imaging scans, possibly including an MRI, to get detailed pictures and measurements of their eye.

Will my child receive any treatment as part of this study?

No, this study is only for gathering information about eye structure. It does not involve any treatment or medication for short-sightedness.

Can my child stop participating at any time?

Yes, you and your child are free to withdraw from the study at any point without it affecting your child's medical care.

How to find out more

Julien Savatosky, Doctor

Always speak to your GP or specialist before deciding to take part in a study.

Interested in taking part?

Register your interest

Share your details and the research team for "Eye Imaging for the Study of Childhood Myopia…" will contact you if you may be eligible. Always speak to your GP before agreeing to take part.

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