AuthorisedTherapeutic confirmatory (Phase III)Interventional

Continuous antibiotic infusion in children

This research study is investigating a different way to give antibiotics to children who have infections. Instead of giving antibiotics a few times a day, this study explores giving them continuously through a drip. The goal is to see if this continuous method can help children recover more quickly, leading to shorter hospital stays and fewer fevers. Researchers also want to find out if it can prevent infections from returning, which means children might not need to come back to the hospital. The study uses well-known antibiotics like Cloxacillin, Benzylpenicillin, and Piperacillin/Tazobactam. This is a Phase 3 study, which means it's a large, important step to confirm if this treatment approach is effective and safe before it can be made widely available.

At a glance

Status

Authorised

Phase

Therapeutic confirmatory (Phase III)

Sponsor

Pirkanmaan hyvinvointialue

Enrolment target

150

Start

16 Feb 2026

Infection disease

What is this study about?

This study is called 'Continuous antibiotic infusion in children.' It's looking at how we can best treat children who have infections. You might be used to antibiotics being given a few times a day, but this study is exploring a different approach: giving the antibiotics non-stop through a drip, which is called a continuous infusion. The main idea is to see if giving antibiotics this way can help children feel better sooner.

The researchers want to find out if this continuous method can reduce the amount of time a child needs to stay in hospital because of their infection. They also want to see if it helps get rid of fevers more quickly and if it stops the infection from coming back once the child goes home. They will be using several common and well-understood antibiotics in this study, such as Cloxacillin, Benzylpenicillin, and Piperacillin/Tazobactam.

This kind of study is known as a 'Phase III' trial. This means it's one of the final stages of testing a treatment before it can be approved for general use. It's a very important step to confirm that the treatment is both safe and effective for many children. The results of this study could help doctors in the future decide the best way to give antibiotics to children with infections.

Key takeaways

Tests a new way of giving antibiotics to children.
Aims for faster recovery and shorter hospital stays.
Uses existing, common antibiotics.
A 'Phase 3' study, meaning it's a key step in testing.
Open to children of all ages with infections.

Who may be eligible?

This study is open to children of all ages who have an infection that requires treatment with antibiotics. The medical team will check carefully to make sure that the type of infection your child has and their overall health makes them suitable for this study.

Both boys and girls are welcome to take part. The goal is to include a wide range of children to understand fully how this treatment works across different age groups and needs.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

Is my child in hospital with an infection?
Does my child need to receive antibiotics?
Am I happy for my child to potentially receive antibiotics through a continuous drip?
Am I comfortable with my child's health being closely monitored as part of a study?

Answer every question to see your result.

What does participation involve?

If your child takes part in this study, they will receive their antibiotics through a continuous drip, just like many patients already do in hospital. The main difference will be how the antibiotics are given. The medical team will closely monitor your child's health throughout their hospital stay. This includes checking their temperature, how long they stay in hospital, and how their infection is responding to the treatment. They will also keep track of any readmissions to the hospital or if the infection seems to come back after your child has gone home. There will be regular checks to make sure your child is doing well, and the total duration of their participation will depend on how long they need antibiotic treatment for their infection.

Potential risks and benefits

Taking part in a study like this could potentially help your child recover from their infection more quickly or spend less time in hospital. However, as with any medical treatment, there's always a small chance of side effects from the medications, even though the antibiotics used are common ones. The study team will explain all known risks to you. You are completely free to withdraw your child from the study at any time, for any reason, without it affecting their medical care.

Locations (1)

Some site locations are approximate. We're improving this — please verify with the trial team before travelling.

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Unverified
Finland

Common questions

What kind of infection is this study for?

This study is for children with various types of infections that need antibiotic treatment.

What does 'continuous infusion' mean?

It means the antibiotic medicine is given slowly and constantly through a drip, rather than in separate doses a few times a day.

Will my child get different antibiotics than they would normally?

The study uses common antibiotics that are already used to treat children's infections. The difference is how they are given.

Is this a new antibiotic?

No, the antibiotics themselves are well-known. This study is testing a new way of giving them.

What happens if we want to stop taking part?

You can withdraw your child from the study at any time, and it won't affect their medical care or treatment.