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RecruitingNAINTERVENTIONAL

Child Cognitive-Affective Resilience Following 13-11 Event : A Pluridisciplinary Study of Intergenerational Transmission of a Traumatic Event

The CARE 13-11 study investigates how significant traumatic events can impact not only those directly involved but also their families, potentially affecting future generations. Researchers are exploring how trauma might be passed down through families, both through biological changes and learned behaviours. This study brings together specialists from various fields, including brain science and social sciences, to get a full picture. It includes families directly affected by the 13-11 event, with children born before it, and also families who weren't exposed, to compare findings and better understand this complex issue. The goal is to learn more about how families adapt after such experiences.

At a glance

Status
Recruiting
Phase
NA
Sponsor
Institut National de la Santé Et de la Recherche Médicale, France
Enrolment target
960
Start
17 Dec 2024
Estimated completion
15 Jan 2027

What is this study about?

The CARE 13-11 study is looking into something called "intergenerational trauma." This is a complex idea that suggests that the effects of a very stressful or traumatic event experienced by one generation can sometimes be passed down and affect future generations within the same family. It's not just about what people see or hear, but also about how their bodies and minds respond to stress, which might then be reflected in their children.

The researchers want to understand how these effects are passed on, whether it's through changes in our biology, like how our stress hormones work, or through behaviours and ways of coping that are learned within the family. This study is unique because it's bringing together different types of scientists – from those who study the brain to those who look at how society works – to get a complete picture of this fascinating and important topic.

To do this, they are looking at families where at least one parent was directly affected by a specific traumatic event that happened on November 13th, 2015. They are also including other family members like uncles, aunts, and cousins who were not directly there but had a close relative who was. To compare, they also have a "control group" of families who were not exposed to these events at all. By studying all these groups, they hope to get answers about how trauma affects families over time and across generations.

Key takeaways

  • The study explores how traumatic events can affect families over generations.
  • It combines different types of research, from brain scans to psychological assessments.
  • Participation involves MRI scans, psychological tests, and stress hormone samples.
  • Both families affected by trauma and those not affected are needed for comparison.
  • The aim is to better understand trauma transmission to help future families.
  • All participants must speak French fluently.

Who may be eligible?

This study is looking for several types of participants, all of whom need to speak French fluently. One main group includes children under 18 who were born before November 13th, 2015, and have at least one parent who was directly present during the traumatic event on that date.

For these children, their parents must give written permission for them to take part. The parents themselves, including those directly exposed and those who were not but whose partner was, can also participate. Additionally, some relatives like aunts, uncles, and cousins of directly affected individuals might be eligible if they meet specific criteria, such as not having been present at the event themselves but having a sibling or aunt/uncle who was.

There's also a comparison group of children who are the same age (under 18, born before November 13th, 2015) but whose family has no connection to the traumatic event. Their parents must also give written consent. The study team will check if you fit all the requirements before you can join.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

  1. Are you a French speaker?
  2. Were you, or your child (if participating), born before November 13th, 2015?
  3. If you're in the 'exposed' group, was at least one parent directly affected by the 13-11 events?
  4. If you're in the 'unexposed' group, is your family completely unconnected to the 13-11 events?
  5. Are both parents willing to give written consent for their child to participate (if applicable)?
Answer every question to see your result.

What does participation involve?

If you decide to take part in this study, you and your child will likely have several assessments. These will include a special type of brain scan called an MRI, which uses magnetic fields to take pictures of the brain – it's completely safe and doesn't involve any radiation. You'll also complete psychological assessments, which are like questionnaires or interviews with a trained professional to understand your feelings and experiences. There will also be cognitive assessments, which are tests designed to look at memory, attention, and problem-solving skills.

Additionally, you might be asked to provide a cortisol sample. Cortisol is a stress hormone, and measuring it can usually be done through simple and painless methods like saliva or hair samples. The study will not involve taking any medication. The full duration of your participation will be explained to you by the study team, including how many visits or assessments you'll need to complete.

Potential risks and benefits

Taking part in any study has potential benefits and risks. A potential benefit of this study is that it helps researchers understand more about how trauma affects families and how people cope across generations. This knowledge could lead to better support for families in the future. As for risks, some of the psychological assessments might involve discussing sensitive or difficult experiences, which could be emotionally challenging for some. However, the study team will be there to support you. Providing samples like saliva or hair is generally very low risk. You are completely free to withdraw from the study at any time, for any reason, without it affecting your medical care.

Locations (1)

  • Umr-S 1077 Nimh
    Verified postcode
    Caen, France· Recruiting

Common questions

What does 'intergenerational trauma' mean?

It means the effects of a shock or very stressful experience can pass down from one generation to the next within a family, affecting how children and later family members respond to things.

Why are they studying children born before the event?

They are looking at children who were conceived and born before November 13th, 2015, to understand how their parents' experiences from that event might have affected them growing up.

What is an MRI scan?

An MRI is a type of scan that uses strong magnets and radio waves to create detailed pictures of the inside of your body, like your brain. It does not use radiation and is generally very safe.

Do I have to speak French to participate?

Yes, all participants in this study, including children and adults, need to have a good command of the French language.

What is the 'control group'?

The control group consists of families who were not exposed to the traumatic events. They are included so researchers can compare their results with those of the exposed families to see the specific effects of the trauma.

How to find out more

Always speak to your GP or specialist before deciding to take part in a study.

Interested in taking part?

Register your interest

Share your details and the research team for "Child Cognitive-Affective Resilience Following 13-11 Event :…" will contact you if you may be eligible. Always speak to your GP before agreeing to take part.

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