A Study of Tirbanibulin Ointment and Diclofenac Sodium Gel for the Treatment of Adult Participants With Actinic Keratosis on the Face or Scalp

To join this study, your doctor will first check if you have actinic keratosis on your face or scalp in a specific area, about the size of a credit card. This area should have 2 to 8 clear actinic keratosis spots, and your skin should generally look healthy in that region.

There are also some important points about your general health. For women who could become pregnant, you'll need to have a negative pregnancy test and use reliable birth control throughout the study. Everyone taking part must be willing to avoid strong sunlight or sunbeds on their face or scalp during the study. You also need to understand what the study involves and be able to follow the study instructions.

You won't be able to join if your actinic keratosis is in certain areas, like your lips, eyelids, ears, or inside your nose. Also, if you have any unhealed wounds or suspicion of other types of skin cancer too close to the treatment area, you wouldn't be able to participate. If your actinic keratosis is very severe, unusual, or has been treated many times before without success, this study might not be suitable for you.

If you decide to take part, you'll be given either the Tirbanibulin ointment or Diclofenac Sodium gel to apply to the actinic keratosis on your face or scalp. Your doctor will explain exactly how and when to use it. You'll have regular check-ups over three years to see how your skin is responding and to monitor for any changes. This will include keeping an eye on the treated area for any signs of skin cancer. You'll also be asked to avoid strong sun or sunbeds on your face or scalp throughout the entire study. The exact number of visits and the duration of medication use will be explained in detail by the study team.