Left Ventricular Thrombus Registry
This study is gathering information about blood clots that can develop in the main pumping chamber of the heart, called the left ventricle. These clots are common after a heart attack or in people with heart failure, affecting about 1 in 6 of them. Such clots can lead to serious health problems, including strokes. We aim to better understand what causes these clots and the best ways to manage them. By collecting blood samples, scan results, and asking about your quality of life, we hope to improve how doctors care for patients with this condition in the future, ultimately benefiting more people.
At a glance
What is this study about?
This research study is focusing on a condition where blood clots form inside the main pumping chamber of your heart, called the left ventricle. This can happen when the heart isn't working as strongly as it should, for example, after a heart attack or in people with heart failure. These clots are a concern because they can sometimes break off and travel to other parts of the body, potentially causing serious issues like a stroke.
Currently, these blood clots are treated with medicines that thin the blood. While these medicines are very important, taking them for a long time can sometimes lead to bleeding problems. Our goal is to gather more information to get a better picture of why these clots form and the most effective ways to manage them without causing other complications.
By understanding more about left ventricular thrombus, we hope to improve the way this condition is diagnosed and treated in the future. This knowledge will not only help the people taking part in this study but also potentially lead to better care and outcomes for many more patients in the UK.
Key takeaways
- Studying blood clots in the heart's main chamber.
- Aims to improve future treatment for this condition.
- Involves collecting routine scan and blood results.
- A small extra blood sample and quality of life questionnaire.
- Participation helps advance understanding for patients.
Who may be eligible?
This study is looking for adults aged 18 or over. You might be able to take part if you currently have a blood clot in your left ventricle, or if you're at a higher risk of developing one. This includes people who have a heart that isn't pumping very well, who have a specific type of heart weakening (called an LV aneurysm), or who have recently had a heart attack.
Unfortunately, you won't be able to join the study if you are under 18 years old or if you are unable to understand and agree to take part.
Could this study suit you?
Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.
- Are you 18 years old or older?
- Do you currently have a blood clot in your left ventricle?
- Have you been told you are at risk of developing a clot in your left ventricle (e.g., severe heart weakness, heart attack)?
- Are you able to understand and agree to take part in the study?
What does participation involve?
If you decide to take part, we will collect information from your routine blood tests and heart scans. You will also be asked to fill out a short questionnaire about your quality of life. Sometimes, if you're already having a routine MRI scan for your heart, we might take a few extra images at that time for our research, but this won't involve any additional procedures for you.
We will also ask for a small blood sample (no more than one tablespoon) specifically for our research. This will be collected at the same time as your routine blood tests when you first join the study, and again around six months later. We'll ask you to complete the quality of life questionnaire again after 12 months, which will be the final step in collecting data for the study. Your participation will be carefully coordinated with your regular hospital visits.
Potential risks and benefits
Locations (1)
- St Bartholomew's HospitalVerified postcodeLondon, United Kingdom· Recruiting
Common questions
What is a 'Left Ventricular Thrombus'?
It's a blood clot that forms inside the left ventricle, which is the main pumping chamber of your heart.
Why is this study important?
It helps us understand why these clots form and the best ways to treat them, which could improve care for many patients in the future.
Will I have to take new medicine?
No, this study only collects information from existing tests and questionnaires; it does not involve new medicines.
How much blood will be taken?
A small amount, no more than one tablespoon, taken at the same time as your routine blood tests.
How long does participation last?
Data collection will mainly occur around your routine visits over a 12-month period.
How to find out more
Always speak to your GP or specialist before deciding to take part in a study.
Interested in taking part?
Discussion
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