Active not recruitingNAINTERVENTIONAL

Cohort of Hospitalized Patients Suspected of Leptospirosis

This study, called COLEPT, is for people admitted to hospital because doctors think they might have leptospirosis. Leptospirosis is an infection caused by bacteria, often spread from animals, and it’s not very well understood. By following patients for a whole year, researchers hope to learn more about how the illness develops, how the body fights it, and how it affects people over time. This information will help doctors understand and treat leptospirosis better in the future. Taking part involves giving blood and urine samples occasionally, which will also be stored in a 'biobank' for future research. This study aims to shed light on a 'neglected' disease.

At a glance

Status

Active not recruiting

Phase

Sponsor

Institut National de la Santé Et de la Recherche Médicale, France

Enrolment target

200

Start

06 Jan 2021

Estimated completion

01 Jul 2027

Leptospirosis

What is this study about?

This study is called COLEPT, and it's designed to learn more about a health problem called leptospirosis. This is an infection caused by bacteria that can make people quite unwell. It often spreads from animals to humans, but many people, including doctors, don't know a lot about it. This study aims to change that by gathering detailed information from people who are in hospital with suspected or confirmed leptospirosis.

Over a year, researchers will keep track of how the illness affects people, how their bodies respond to the infection, and any other health information that might be important. The main goal is to understand leptospirosis much better, including its causes, symptoms, and long-term effects. This will help doctors diagnose and treat it more effectively in the future, improving care for patients.

By taking part, you would be helping medical science. The information collected from volunteers in this study can lead to new discoveries and better ways to care for people with leptospirosis around the world. It's an important step in tackling what is currently a 'neglected' disease.

Key takeaways

The study looks at people in hospital with suspected or confirmed leptospirosis.
It aims to understand this bacterial infection better over a one-year period.
Participation involves giving blood and urine samples.
No new medications are given as part of the study.
Information from the study could lead to better future treatments.
You can stop participating at any time.

Who may be eligible?

To be considered for this study, you would need to be in hospital because doctors think you might have leptospirosis, or already know you have it based on tests. Your symptoms must have started within the last three weeks.

You also need to have health insurance, which is a common requirement for many medical studies. Unfortunately, if you or your family (if you're unable to decide yourself, for example, if you're in a coma or intensive care) say no to taking part, then you wouldn't be able to join the study.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

Are you currently in hospital because doctors suspect or have confirmed leptospirosis?
Did your symptoms start within the last 21 days (three weeks)?
Do you have health insurance?
Have you (or your family, if you can't decide) agreed to consider participating?

Answer every question to see your result.

What does participation involve?

If you decide to take part in this study, the doctors and nurses will regularly collect blood and urine samples from you while you are in hospital and during follow-up over one year. These samples will be tested straight away and also stored in a special collection called a 'biobank' for future research. You won't be given any new medications or treatments specially for the study; the focus is on gathering information about your illness. The total duration of your participation, meaning how long they will follow your health and collect samples, will be for one year.

Potential risks and benefits

Taking part in this study could help doctors and researchers understand leptospirosis better, which might lead to improved diagnosis and treatment for others in the future. The main risks involve giving blood samples, which might cause a little discomfort, bruising, or, very rarely, an infection. All samples will be taken by trained professionals to minimise any risks. You are free to withdraw from the study at any time, for any reason, without it affecting your medical care.

Locations (4)

Groupe Hospitalier Est Réunion (GHER)
Verified postcode
Saint-Benoît, France
CHU de La Réunion site Nord
Verified postcode
Saint-Denis, France
Centre Hospitalier Ouest Réunion (CHOR)
Verified postcode
Saint-Paul, France
CHU de La Réunion site Sud (GHSR)
Verified postcode
Saint-Pierre, France

Common questions

What is leptospirosis?

It's an infection caused by bacteria, often spread from animals, that can make people very unwell.

Why is this study important?

It aims to learn much more about leptospirosis, which is not well understood, to help improve care for future patients.

Will I get new medicine in this study?

No, you won't be given any special study medications. The study focuses on collecting information and samples.

How long will I be in the study?

You will be followed by the study for a total of one year.

Can I leave the study if I change my mind?

Yes, you can choose to leave the study at any point without it affecting your medical care.