RecruitingNAINTERVENTIONAL

BeSpoke Decision Support for Patients With Newly Diagnosed Localised Prostate Cancer

This study is investigating a new tool called 'BeSpoke Decision Support' for men who have recently been told they have localised prostate cancer. This tool is designed to give personalised information to help them understand their treatment options better and make a confident decision about their care. Researchers want to see if using this tool alongside standard information helps reduce confusion or worry when choosing treatments. Some men will use the new tool, while others will receive standard information only. Everyone will complete questionnaires to share their experiences and how they are feeling over time. The study aims to make sure men feel supported and informed when facing important treatment choices.

At a glance

Status

Recruiting

Phase

Sponsor

University College, London

Enrolment target

346

Start

22 Jul 2026

Estimated completion

01 Dec 2028

Localised Prostate Cancer

What is this study about?

When you're diagnosed with localised prostate cancer, deciding on the best treatment for you can be a big step, and it's normal to feel a bit overwhelmed or unsure. This study is testing a new approach called 'BeSpoke Decision Support' to see if it can make this important decision easier and clearer for men like you.

At the moment, when you receive a diagnosis, you'll get standard information, perhaps a booklet from Prostate Cancer UK, and have appointments with doctors to discuss your choices. This study wants to see if adding something extra – the BeSpoke Decision Support tool – can improve that process. This tool is designed to give you consistent, up-to-date information, personalised predictions about how different treatments might affect you based on your specific cancer and health, and help you think about what matters most to you when choosing a treatment.

The study will involve some men receiving the standard information and support, while others will also get access to this new BeSpoke tool. Researchers want to compare these two groups to understand if the BeSpoke tool truly helps men feel more confident and less conflicted about their treatment decision. They'll also follow up with participants for a year to see how their quality of life, including things like urinary and sexual health, is affected by their choices.

Key takeaways

Tests a new tool to help men with localised prostate cancer choose treatment.
Aims to reduce confusion and improve confidence in treatment decisions.
Compares a new personalised tool with standard information.
Involves answering questionnaires over a year.
Participants can choose their own treatment.
Not suitable if cancer has spread or you're in another specific study.

Who may be eligible?

This study is for men who have recently been diagnosed with localised prostate cancer. This means the cancer is only in the prostate and hasn't spread to other parts of the body. You would also need to be suitable for at least two different treatment options, such as active surveillance, focal therapy, surgery (radical prostatectomy), or radiotherapy.

There are a few reasons why someone might not be able to join. For example, if your cancer is very low risk and doesn't require active treatment, or if you have serious health problems that would make treatment difficult. You also can't join if there's a strong suspicion that your cancer has already spread, or if you're already in another study where your treatment is chosen for you, rather than you making the decision.

It's important that you can understand the information and give your consent to take part. While the BeSpoke tool is in English, if you have a family member or friend who can help you with the language, you might still be able to join.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

Have I recently been diagnosed with localised prostate cancer?
Am I suitable for at least two different treatment options?
Can I understand the study information and provide consent?
Do I need help to understand the BeSpoke tool in English?
Is my cancer definitely localised (not spread)?
Am I already in another study where treatment is assigned to me?

Answer every question to see your result.

What does participation involve?

If you decide to take part in this study, the first step is to give your informed consent. You'll then be randomly placed into one of two groups. One group will receive the usual care and information you'd expect when deciding on prostate cancer treatment. The other group will receive this standard care plus access to the new BeSpoke Decision Support tool which provides extra personalised information.

Before you make your treatment decision, and then again after you've made it, you will be asked to fill out questionnaires. These questionnaires will ask about your urinary, sexual, and bowel health, as well as your experience with making the treatment decision. You'll also complete these questionnaires at 3, 6, and 12 months after your treatment starts. Some patients may also be invited for an interview to talk about their decision-making experience. Healthcare professionals involved in the study will also be interviewed to share their perspective.

Potential risks and benefits

Taking part in this study may offer the benefit of potentially feeling more informed and confident in your treatment decision, especially if you're in the group using the BeSpoke tool. However, there are no guarantees of direct medical benefits. The main 'risk' involves the time commitment needed to complete questionnaires and potentially an interview. As with any study, you are free to withdraw at any time without giving a reason, and this will not affect your usual medical care.

Locations (1)

University College London Hospitals NHS Foundation Trust
Verified postcode
London, United Kingdom· Recruiting

Common questions

What is 'localised prostate cancer'?

It means the cancer is only found within the prostate gland and has not spread to other parts of the body.

What is 'Standard of Care' (SOC)?

This refers to the usual and widely accepted information and care you would receive from your doctors for your condition.

Will I get to choose my treatment?

Yes, this study is designed to help you make an informed choice between suitable treatment options, not to choose for you.

What if I don't speak English well?

If you have a family member or friend who can help you understand and use the BeSpoke tool, you might still be able to take part.

How long will I be involved in the study?

You will complete questionnaires at the beginning, after your treatment decision, and then at 3, 6, and 12 months after your treatment starts, so up to a year of follow-up.

How to find out more

Davide Maffei, MD

d.maffei@ucl.ac.uk +44 (0)20 7679 2000 Official trial record

Always speak to your GP or specialist before deciding to take part in a study.