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A Study to Evaluate Patient-Reported Satisfaction, Effectiveness, and Safety of Atezolizumab in Participants Treated in Routine Clinical Practice

This study aims to understand how effective and safe a medicine called Atezolizumab is for people with certain types of lung cancer or liver cancer. It also wants to know how satisfied patients are with this treatment and how it affects their daily lives. Unlike studies where treatment is strictly controlled, this one looks at Atezolizumab as it's given in regular everyday hospital or clinic settings. This helps doctors understand the real-world experience of patients, including their well-being and any side effects, to ensure the medicine is working as expected for these conditions.

At a glance

Status
Recruiting
Sponsor
Hoffmann-La Roche
Enrolment target
700
Start
15 Jul 2025
Estimated completion
31 Dec 2028

What is this study about?

This study is about a medicine called Atezolizumab, which is used to treat certain types of lung cancer and a type of liver cancer. Researchers want to find out how well this medicine works, how safe it is, and importantly, how patients feel about their treatment and their overall quality of life while taking it. This is not like a traditional clinical trial where people are given a new medicine or a fake medicine under strict conditions. Instead, this study observes how Atezolizumab is used by patients in their normal hospital or clinic care, as prescribed by their doctors.

The main goal is to gather information from people already receiving Atezolizumab to understand their real-world experiences. This includes looking at things like how satisfied they are with the way the medicine is given (especially the under-the-skin version), how it impacts their daily life and health, and if they experience any side effects.

By collecting this information, doctors and researchers can get a clearer picture of how Atezolizumab performs outside of highly controlled study environments. This helps them ensure the medicine is effective and well-tolerated for people with these specific cancers, and that patients are generally happy with their treatment experience.

Key takeaways

  • This study looks at how Atezolizumab works for lung or liver cancer in everyday medical practice.
  • It checks how satisfied patients are with their treatment and their quality of life.
  • You would continue your regular Atezolizumab treatment; nothing new will be given.
  • Participation mainly involves filling out questionnaires about your experience.
  • Your feedback helps doctors understand real-world patient experiences.
  • You can stop participating at any time without affecting your medical care.

Who may be eligible?

To join this study, you would need to have certain types of lung cancer or a specific type of liver cancer for which Atezolizumab is already an approved treatment by the NHS. Your doctor would confirm if your cancer type fits these requirements, such as whether it's early or advanced stage, and if you haven't received other specific treatments recently that would prevent you from taking part.

You would not be able to join if you are already taking Atezolizumab as part of another research study, or if you are receiving other cancer treatments at the very same time. The study also needs to make sure you are getting Atezolizumab in the usual way that doctors prescribe it. Importantly, you must be willing to fill out questionnaires about how you feel and your satisfaction with the treatment.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

  1. Do I have a type of lung cancer or liver cancer for which Atezolizumab is approved?
  2. Am I already receiving Atezolizumab, or am I about to start it?
  3. Am I willing to fill out questionnaires about my treatment and how I feel?
  4. Am I not currently part of another clinical trial for Atezolizumab?
Answer every question to see your result.

What does participation involve?

If you join this study, you won't be given a new or different treatment. You will continue to receive Atezolizumab as your doctor has already prescribed it for your cancer, following the standard care you would normally receive. The main part of your participation will involve completing questionnaires regularly. These questionnaires will ask about your satisfaction with the treatment, your general health, and how the treatment affects your daily life. The study will also collect information from your existing medical records about how your treatment is progressing and any side effects you might experience. There will be no extra visits or tests specifically for this study outside of your usual appointments.

Potential risks and benefits

Since this study observes your treatment as part of your normal care, there are generally no extra medical risks beyond those already associated with Atezolizumab itself, which your doctor will have discussed with you. The main potential benefit is that by sharing your experience, you contribute valuable information that helps doctors better understand how Atezolizumab works and affects patients in real-world settings. This can help improve care for others in the future. You are free to stop participating in the study and completing questionnaires at any time without affecting your medical treatment.

Locations (91)

Some site locations are approximate. We're improving this — please verify with the trial team before travelling.
  • Landesklinikum Krems
    Verified postcode
    Krems, Austria· Recruiting
  • Ordensklinikum Linz Elisabethinen
    Verified postcode
    Linz, Austria· Recruiting
  • Krankenhaus Nord - Klinik Floridsdorf
    Verified postcode
    Vienna, Austria· Recruiting
  • Klinikum Wels-Grieskirchen
    Verified postcode
    Wels, Austria· Recruiting
  • CHIREC
    Verified postcode
    Auderghem, Belgium· Recruiting
  • AZ Sint Lucas (Sint Lucas)
    Verified postcode
    Ghent, Belgium· Recruiting
  • CHU HELORA - Hôpital de la Louvière - Site Jolimont
    Verified postcode
    Haine-Saint-Paul, Belgium· Recruiting
  • CHC MontLégia
    Verified postcode
    Liège, Belgium· Recruiting
  • ZNA Jan Palfijn
    Verified postcode
    Merksem, Belgium· Recruiting
  • CHU UCL Mont-Godinne
    Unverified
    Mont-godinne, Belgium· Recruiting
  • Multiprofile Hospital for Active Treatment Uni Hospital
    Verified postcode
    Panagyurishte, Bulgaria· Recruiting
  • Complex Oncological Center-Ruse EOOD
    Verified postcode
    Rousse, Bulgaria· Recruiting

Common questions

What is Atezolizumab?

Atezolizumab is a medicine used to treat certain types of cancer, including some lung cancers and a specific type of liver cancer.

Will I get a different treatment in this study?

No, you will keep receiving the Atezolizumab treatment your doctor has already prescribed for you, as part of your normal care.

What do I need to do if I join?

Mainly, you'll be asked to fill out questionnaires about your health, treatment, and how satisfied you are with it.

Will there be extra doctor visits?

No, your participation in the study won't require any extra visits beyond your usual medical appointments.

Can I stop participating if I change my mind?

Yes, you can choose to stop taking part in the study at any time without it affecting your medical care.

How to find out more

Reference Study ID Number: MO45893 https://forpatients.roche.com/

Always speak to your GP or specialist before deciding to take part in a study.

Interested in taking part?

Register your interest

Share your details and the research team for "A Study to Evaluate Patient-Reported Satisfaction, Effective…" will contact you if you may be eligible. Always speak to your GP before agreeing to take part.

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