A Clinical Study of MK-1045 in People With Non-Hodgkin Lymphoma (MK-1045-008)

This study is looking for adults aged 18 or older who have either follicular lymphoma (FL) or diffuse large B-cell lymphoma (DLBCL).

To be considered, your lymphoma must have come back after or not responded to at least two previous treatments. If you have DLBCL, you would also need to have progressed after or not be suitable for a stem cell transplant or CAR-T cell therapy. Researchers will also need to review a sample of your tumour tissue. Certain other conditions, like poorly controlled HIV, Hepatitis B or C, or serious heart problems, would mean you couldn't take part. Also, if you've had an organ transplant or certain other serious health issues, you wouldn't be able to join this study.

The detailed information about what taking part involves is not fully available in this brief summary. However, in a clinical trial like this, you would typically have regular visits to the hospital or clinic. These visits would include physical exams, blood tests, and scans (like CT scans) to monitor your health and how the treatment is working. You would receive the study medication, MK-1045, according to a specific schedule decided by the study doctors. There would also be follow-up appointments after your treatment ends to ensure your health is stable. The total duration of your participation would depend on the study's plan and your individual response.