RecruitingOBSERVATIONAL

Research and Development of Novel Quantitative Magnetic Resonance Imaging (MRI) Techniques in a Single Scan for Multiple Organ Application

This research project aims to improve how MRI scans work, specifically for looking at multiple organs at once. We're developing new techniques to make MRI images clearer and more reliable. To do this, we'll be scanning healthy volunteers and checking if these new methods provide consistent results over time. The goal is to make future MRI scans more effective for understanding and monitoring various health conditions. It's an observational study, meaning researchers will collect information and images without giving any new treatments or medicines. This project could eventually lead to quicker and more accurate diagnoses for many people.

At a glance

Status

Recruiting

Sponsor

Perspectum

Enrolment target

600

Start

15 Nov 2021

Estimated completion

30 Apr 2031

Multiple

What is this study about?

Imagine getting an MRI scan that could look at lots of different parts of your body all at once, giving doctors a full picture without needing multiple appointments. That's what this research is trying to achieve! We're working on new ways to use MRI scanners to get better images of various organs in a single scan. Think of it like upgrading a camera to take much clearer and more reliable photos.

The main goal is to make MRI scanning methods more accurate and consistent. This means that if you had a scan today and another one next month, the results would be very similar, helping doctors track changes in your health more precisely. To do this, we need to test these new techniques on healthy volunteers. By seeing how well these methods work in people who don't have specific health problems, we can make sure they are ready to be used in future medical care.

This study is important because better, more consistent MRI scans could lead to earlier and more accurate diagnoses for many different health issues. It could also make monitoring your health easier and more effective for your doctors. By helping us fine-tune these new methods, participants are contributing to the future of medical imaging.

Key takeaways

Aims to improve MRI scans for multiple organs in one go.
Tests new MRI techniques on healthy volunteers for better imaging.
Study is observational, no new treatments or medications given.
Participation involves a screening call, health checks, and MRI scans.
Crucial for advancing medical imaging and future diagnoses.
You can withdraw from the study at any time without consequence.

Who may be eligible?

To be part of this study, you need to be an adult aged 18 or over. You should be happy and able to understand what the study involves and give your full permission to take part. It's also important that you can speak and understand English well enough to talk with the research team and follow all the study instructions. Lastly, you must be willing and able to safely have an MRI scan.

There are some reasons why you might not be able to join. For example, if you have any metal in your body that isn't safe for an MRI, such as a pacemaker, certain types of implants, or shrapnel. Pregnancy also means you can't have an MRI for this study. If you get very anxious in small spaces (severe claustrophobia) or have a very high Body Mass Index (BMI usually over 40-45) which might make the scan difficult or uncomfortable, you might not be suitable. The research team will do a health check to make sure it's safe for you to participate.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

Are you 18 years old or older?
Can you understand the study information and give consent?
Do you speak and understand English well enough to communicate with the team?
Are you willing and able to have an MRI scan?
Do you have any metal in your body that would make an MRI unsafe? (e.g., pacemaker, certain implants)
Are you pregnant or might you be pregnant?

Answer every question to see your result.

What does participation involve?

If you decide to take part, your journey will start with a screening call, usually over the phone. During this call, the team will explain everything fully, get your consent electronically, and ask some questions about your health to make sure you're suitable. Once approved, you'll have an initial visit where we'll measure your height, weight, and waist. You'll also discuss your health history with the team and have an MRI scan. There might also be some extra standard health checks during this visit.

Some participants will then be asked to come back for additional visits, possibly up to eight more, which would involve repeating the MRI scan and updating your health information. The study aims to recruit up to 600 participants, and volunteers are being found through various channels like Perspectum's own database, partner sites, social media (Facebook, Instagram), Perspectum's website, and charities. You won't receive any new medications or treatments as part of this study; it's purely about collecting information and images.

Potential risks and benefits

By taking part, you'll be helping medical science develop better ways to use MRI scans, which could benefit many patients in the future. The main potential risk comes from the MRI scan itself, but we will carefully check to make sure it's safe for you before you start. For example, people with certain metal implants cannot have an MRI. The team will explain all potential inconveniences, such as lying still in the scanner. You are free to withdraw from the study at any time, for any reason, without it affecting your medical care.

Locations (1)

Some site locations are approximate. We're improving this — please verify with the trial team before travelling.

Gemini One, 5520 John Smith Drive
Verified postcode
Oxford, United Kingdom· Recruiting

Common questions

What is an MRI scan?

An MRI scan uses strong magnets and radio waves to create detailed pictures of the inside of your body without using X-rays. It's a common and safe imaging test.

Will I receive any new treatments or medications?

No, this study is observational. You won't be given any new treatments or medications. We are only collecting information and images.

How many times might I need to visit?

You'll have an initial screening call and one main visit. Some participants may be asked to come back for up to eight additional visits, primarily for repeat MRI scans.

What if I feel uncomfortable during the MRI?

You'll be in communication with the MRI staff throughout the scan. If you feel uncomfortable, you can let them know, and they can stop the scan if needed.

Who is funding this research?

This research is being conducted by Perspectum, a company focused on medical imaging research and development. They are the primary sponsor of the trial.

How to find out more

Soubera M Rymell, MSc

soubera.rymell@perspectum.com 00447313272482 Official trial record

Always speak to your GP or specialist before deciding to take part in a study.